Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

SM Gygli, S Borrell, A Trauner… - FEMS microbiology …, 2017 - academic.oup.com
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …

Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Evolutionary mechanisms shaping the maintenance of antibiotic resistance

P Durão, R Balbontín, I Gordo - Trends in microbiology, 2018 - cell.com
Antibiotics target essential cellular functions but bacteria can become resistant by acquiring
either exogenous resistance genes or chromosomal mutations. Resistance mutations …

Combination effects of antimicrobial peptides

G Yu, DY Baeder, RR Regoes… - Antimicrobial agents and …, 2016 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are ancient and conserved across the tree of life. Their
efficacy over evolutionary time has been largely attributed to their mechanisms of killing. Yet …

Urban metagenomics uncover antibiotic resistance reservoirs in coastal beach and sewage waters

P Fresia, V Antelo, C Salazar, M Giménez… - Microbiome, 2019 - Springer
Background Microbial communities present in environmental waters constitute a reservoir
for antibiotic-resistant pathogens that impact human health. For this reason, a diverse variety …

Cross-resistance of the pathogenic fungus Alternaria alternata to fungicides with different modes of action

LN Yang, MH He, HB Ouyang, W Zhu, ZC Pan, QJ Sui… - BMC microbiology, 2019 - Springer
Background Cross-resistance, a phenomenon that a pathogen resists to one antimicrobial
compound also resists to one or several other compounds, is one of major threats to human …

[HTML][HTML] Using ecological coexistence theory to understand antibiotic resistance and microbial competition

AD Letten, AR Hall, JM Levine - Nature ecology & evolution, 2021 - nature.com
Tackling antibiotic resistance necessitates deep understanding of how resource competition
within and between species modulates the fitness of resistant microbes. Recent advances in …

The influence of biofilm formation and multidrug resistance on environmental survival of clinical and environmental isolates of Acinetobacter baumannii

C Greene, G Vadlamudi, D Newton, B Foxman… - American journal of …, 2016 - Elsevier
Background Acinetobacter baumannii is a gram-negative, opportunistic pathogen. Its ability
to form biofilm and increasing resistance to antibiotic agents present challenges for infection …

[HTML][HTML] Theory of microbial coexistence in promoting soil–plant ecosystem health

N Zhang, N Nunan, PR Hirsch, B Sun, J Zhou… - Biology and Fertility of …, 2021 - Springer
A healthy soil plant continuum is critical for maintaining agroecosystem functions and
ensuring food security, which is the basis of sustainable agricultural development. Diverse …

Cross-feeding modulates the rate and mechanism of antibiotic resistance evolution in a model microbial community of Escherichia coli and Salmonella enterica

EM Adamowicz, M Muza, JM Chacón… - PLoS …, 2020 - journals.plos.org
With antibiotic resistance rates on the rise, it is critical to understand how microbial species
interactions influence the evolution of resistance. In obligate mutualisms, the survival of any …