Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
Evolutionary mechanisms shaping the maintenance of antibiotic resistance
Antibiotics target essential cellular functions but bacteria can become resistant by acquiring
either exogenous resistance genes or chromosomal mutations. Resistance mutations …
either exogenous resistance genes or chromosomal mutations. Resistance mutations …
Combination effects of antimicrobial peptides
Antimicrobial peptides (AMPs) are ancient and conserved across the tree of life. Their
efficacy over evolutionary time has been largely attributed to their mechanisms of killing. Yet …
efficacy over evolutionary time has been largely attributed to their mechanisms of killing. Yet …
Urban metagenomics uncover antibiotic resistance reservoirs in coastal beach and sewage waters
Background Microbial communities present in environmental waters constitute a reservoir
for antibiotic-resistant pathogens that impact human health. For this reason, a diverse variety …
for antibiotic-resistant pathogens that impact human health. For this reason, a diverse variety …
Cross-resistance of the pathogenic fungus Alternaria alternata to fungicides with different modes of action
LN Yang, MH He, HB Ouyang, W Zhu, ZC Pan, QJ Sui… - BMC microbiology, 2019 - Springer
Background Cross-resistance, a phenomenon that a pathogen resists to one antimicrobial
compound also resists to one or several other compounds, is one of major threats to human …
compound also resists to one or several other compounds, is one of major threats to human …
[HTML][HTML] Using ecological coexistence theory to understand antibiotic resistance and microbial competition
Tackling antibiotic resistance necessitates deep understanding of how resource competition
within and between species modulates the fitness of resistant microbes. Recent advances in …
within and between species modulates the fitness of resistant microbes. Recent advances in …
The influence of biofilm formation and multidrug resistance on environmental survival of clinical and environmental isolates of Acinetobacter baumannii
C Greene, G Vadlamudi, D Newton, B Foxman… - American journal of …, 2016 - Elsevier
Background Acinetobacter baumannii is a gram-negative, opportunistic pathogen. Its ability
to form biofilm and increasing resistance to antibiotic agents present challenges for infection …
to form biofilm and increasing resistance to antibiotic agents present challenges for infection …
[HTML][HTML] Theory of microbial coexistence in promoting soil–plant ecosystem health
A healthy soil plant continuum is critical for maintaining agroecosystem functions and
ensuring food security, which is the basis of sustainable agricultural development. Diverse …
ensuring food security, which is the basis of sustainable agricultural development. Diverse …
Cross-feeding modulates the rate and mechanism of antibiotic resistance evolution in a model microbial community of Escherichia coli and Salmonella enterica
EM Adamowicz, M Muza, JM Chacón… - PLoS …, 2020 - journals.plos.org
With antibiotic resistance rates on the rise, it is critical to understand how microbial species
interactions influence the evolution of resistance. In obligate mutualisms, the survival of any …
interactions influence the evolution of resistance. In obligate mutualisms, the survival of any …