Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …
pollutants and are known to exert severe adverse impacts on the nervous system even at …
[HTML][HTML] Sex and gender considerations in Alzheimer's disease: The Women's Brain Project contribution
L Castro-Aldrete, MV Moser, G Putignano… - Frontiers in Aging …, 2023 - frontiersin.org
The global population is expected to have about 131.5 million people living with Alzheimer's
disease (AD) and other dementias by 2050, posing a severe health crisis. Dementia is a …
disease (AD) and other dementias by 2050, posing a severe health crisis. Dementia is a …
Incidence of syndromes associated with frontotemporal lobar degeneration in 9 European countries
Importance Diagnostic incidence data for syndromes associated with frontotemporal lobar
degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic …
degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic …
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease
JM Eissman, L Dumitrescu, ER Mahoney, AN Smith… - Brain, 2022 - academic.oup.com
Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the
presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are …
presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are …
[HTML][HTML] Neuroimaging in frontotemporal dementia: heterogeneity and relationships with underlying neuropathology
Frontotemporal dementia encompasses a group of clinical syndromes defined
pathologically by degeneration of the frontal and temporal lobes. Historically, these …
pathologically by degeneration of the frontal and temporal lobes. Historically, these …
[HTML][HTML] Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system
Introduction Progranulin (PGRN) is a secreted glycoprotein, the expression of which is
linked to several neurodegenerative diseases. Although its specific function is still unclear …
linked to several neurodegenerative diseases. Although its specific function is still unclear …
[图书][B] A blueprint for dementia research
World Health Organization - 2022 - books.google.com
Research and innovation are integral parts of the global response to dementia. Yet, the
Global status report on the public health response to dementia shows that despite some …
Global status report on the public health response to dementia shows that despite some …
[HTML][HTML] Sex influences clinical phenotype in frontotemporal dementia
M Pengo, A Alberici, I Libri, A Benussi, Y Gadola… - Neurological …, 2022 - Springer
Introduction Frontotemporal dementia (FTD) encompasses a wide spectrum of genetic,
clinical, and histological findings. Sex is emerging as a potential biological variable …
clinical, and histological findings. Sex is emerging as a potential biological variable …
New developments of biofluid‐based biomarkers for routine diagnosis and disease trajectories in frontotemporal dementia
M Del Campo, H Zetterberg, S Gandy… - Alzheimer's & …, 2022 - Wiley Online Library
Frontotemporal dementia (FTD) covers a spectrum of neurodegenerative disorders with
different phenotypes, genetic backgrounds, and pathological states. Its clinicopathological …
different phenotypes, genetic backgrounds, and pathological states. Its clinicopathological …
Gender/sex differences in the association of mild behavioral impairment with cognitive aging
Background: While the gender/sex differences in neuropsychiatric symptoms in dementia
population are well described, gender/sex differences in mild behavioral impairment (MBI) in …
population are well described, gender/sex differences in mild behavioral impairment (MBI) in …