A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Amyloid-beta (Aß) and hyperphosphorylated tau are hallmark lesions of Alzheimer's disease
(AD). However, the loss of synapses and dysfunctions of neurotransmission are more …

Objective Vaping may increase the cytotoxic effects of e-cigarette liquid (ECL). We
compared the effect of unvaped ECL to e-cigarette vapour condensate (ECVC) on alveolar …

Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

Inflammation can cause damage and even death. What controls this primitive and potentially
lethal innate immune response to injury and infection? Molecular and neurophysiological …

This Opinion article discusses emerging evidence of direct contributions of nicotine to
cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding …

Alzheimer's Disease (AD) is the major form of senile dementia, characterized by neuronal
loss, extracellular deposits, and neurofibrillary tangles. It is accompanied by a loss of …

Nicotinic receptors—a family of ligand-gated ion channels that mediate the effects of the
neurotransmitter acetylcholine—are among the most well understood allosteric membrane …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …