A fundamental subdivision of nociceptive sensory neurons is named after their unique
sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin …

In this article, we propose that differences in COVID-19 morbidity may be associated with
transient receptor potential ankyrin 1 (TRPA1) and/or transient receptor potential vanilloid 1 …

BACKGROUND Chronic pain is a debilitating illness with currently limited therapy, in part
due to difficulties in translating treatments derived from animal models to patients. The …

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal cation channel that is
activated by electrophilic irritants, oxidative stress, cold temperature, and GPCR signaling …

Although TRPV1 ion channel has been attracting researchers' attention for many years, its
functions in animal organisms, the principles of regulation, and the involvement in …

Abstract The World Health Organization lists air pollution as one of the top five risks for
developing chronic non-communicable disease, joining tobacco use, harmful use of alcohol …

Use of chemotherapy drug oxaliplatin is associated with painful peripheral neuropathy that
is exacerbated by cold. Remodeling of ion channels including TRP channels in dorsal root …

Multiple chemical sensitivity (MCS) is a complex medical condition associated with low dose
chemical exposures. MCS is characterized by diverse features and common comorbidities …

Over the last 17 years since its cloning in 2003, the receptor-channel TRPA1 has received
increasing attention due to its polymodal features and prominent role in pain signaling in a …

Transient receptor potential ankyrin-1 (TRPA1) is an ion channel mediating pain and cough
signals in sensory neurons. We and others have shown that TRPA1 is also expressed in …