Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on …

J van der Velden, FW Asselbergs… - Cardiovascular …, 2022 - academic.oup.com
Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

How does hemodynamics affect rupture tissue mechanics in abdominal aortic aneurysm: Focus on wall shear stress derived parameters, time-averaged wall shear …

O Mutlu, HE Salman, H Al-Thani, A El-Menyar… - Computers in biology …, 2023 - Elsevier
An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …

Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows

KAS Boster, S Cai… - Proceedings of the …, 2023 - National Acad Sciences
Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste
clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …

Hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions

M Kadem, L Garber, M Abdelkhalek… - IEEE Reviews in …, 2022 - ieeexplore.ieee.org
Cardiovascular disease is a deadly global health crisis that carries a substantial financial
burden. Innovative treatment and management of cardiovascular disease straddles …

[HTML][HTML] Medical image-based computational fluid dynamics and fluid-structure interaction analysis in vascular diseases

Y He, H Northrup, H Le, AK Cheung… - … in Bioengineering and …, 2022 - frontiersin.org
Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

[HTML][HTML] Modeling dynamics of the cardiovascular system using fluid-structure interaction methods

F Syed, S Khan, M Toma - Biology, 2023 - mdpi.com
Simple Summary Fluid-structure interaction algorithms are utilized to examine how the
human circulatory system functions by simulating blood flow and capturing mechanical …

Characterizing Flow and Transport in Biological Vascular Systems: A Review from Physiological and Chemical Engineering Perspectives

Z Chen, LT Zhu, ZH Luo - Industrial & Engineering Chemistry …, 2023 - ACS Publications
The investigation of biological fluidic mechanisms is a persistent topic of interest and offers
valuable inspiration to address the challenges confronting chemical engineering …

Underlying mechanism of hemodynamics and intracranial aneurysm

H Tang, Q Wang, F Xu, X Zhang, Z Zeng… - Chinese …, 2022 - mednexus.org
In modern society, subarachnoid hemorrhage, mostly caused by intracranial aneurysm
rupture, is accompanied by high disability and mortality rate, which has become a major …

[HTML][HTML] On the potential self-amplification of aneurysms due to tissue degradation and blood flow revealed from FSI simulations

H Wang, D Balzani, V Vedula, K Uhlmann… - Frontiers in …, 2021 - frontiersin.org
Tissue degradation plays a crucial role in the formation and rupture of aneurysms. Using
numerical computer simulations, we study the combined effects of blood flow and tissue …

[HTML][HTML] A fluid-structure interaction model accounting arterial vessels as a key part of the blood-flow engine for the analysis of cardiovascular diseases

H Cheng, G Li, J Dai, K Zhang, T Xu, L Wei… - … in Bioengineering and …, 2022 - frontiersin.org
According to the classical Windkessel model, the heart is the only power source for blood
flow, while the arterial system is assumed to be an elastic chamber that acts as a channel …