Interactions between polyoxometalates and biological systems: from drug design to artificial enzymes

LS Van Rompuy, TN Parac-Vogt - Current opinion in biotechnology, 2019 - Elsevier
Polyoxometalates have long been studied in a variety of biological applications. Interactions
between the highly charged POM molecules and biological molecules frequently occur …

[HTML][HTML] Overview of Wells-Dawson Polyoxometalates: from structure and functionalization to application

D Nowicka, N Vadra, E Wieczorek-Szweda… - Coordination Chemistry …, 2024 - Elsevier
Abstract Wells-Dawson polyoxometalates (WD POMs) are an important subgroup within the
diverse family of POMs. In the last two decades, there has been remarkable progress in the …

Chitosan nanogels as nanocarriers of polyoxometalates for breast cancer therapies

L Pérez-Álvarez, L Ruiz-Rubio, B Artetxe… - Carbohydrate …, 2019 - Elsevier
Polyoxometalates (POMs) have been revealed as interesting antitumor agents inhibiting the
action of Sox2 transcription factor, which reduces the risk of metastasis during hormonal …

Preparation and characterization of biodegradable κ-carrageenan based anti-bacterial film functionalized with Wells-Dawson polyoxometalate

F Zhou, D Wang, J Zhang, J Li, D Lai, S Lin, J Hu - Foods, 2022 - mdpi.com
In the present study, an anti-bacterial film (Carr/POM film) was prepared through the
incorporation of Wells-Dawson polyoxometalate K6 [Mo18O62P2] into κ-carrageenan-based …

K6[P2Mo18O62] as DNase-Mimetic Artificial Nucleases to Promote Extracellular Deoxyribonucleic Acid Degradation in Bacterial Biofilms

S Lin, J Li, F Zhou, BK Tan, B Zheng, J Hu - ACS omega, 2023 - ACS Publications
In the current study, the DNase-like activity of the Dawson-type polyoxometalate K6
[P2Mo18O62] was explored. The obtained findings demonstrated that K6 [P2Mo18O62] …

Functional genomics of AP-2α and AP-2γ in cancers: in silico study

D Kołat, Ż Kałuzińska, M Orzechowska… - BMC Medical …, 2020 - Springer
Background Among all causes of death, cancer is the most prevalent and is only outpaced
by cardiovascular diseases. Molecular theory of carcinogenesis states that apoptosis and …

WWOX loses the ability to regulate oncogenic AP-2γ and synergizes with tumor suppressor AP-2α in high-grade bladder cancer

D Kołat, Ż Kałuzińska, AK Bednarek, E Płuciennik - Cancers, 2021 - mdpi.com
Simple Summary A prognostic factor of bladder cancer which can benefit from research on
molecular markers is the histologic grade. WWOX, AP-2α and AP-2γ are known to have a …

Polyoxometalate K6[P2Mo18O62] Inactivates Escherichia coli O157:H7 by Inducing recA Expression and Apoptosis-like Bacterial Death

S Lin, Z Lin, F Zhou, D Wang, B Zheng… - International Journal of …, 2023 - mdpi.com
Polyoxometalates have emerged as promising bactericidal agents. In the current study, the
bactericidal activity of polyoxometalate K6 [P2Mo18O62] against Escherichia coli (E. coli) …

Lindqvist-type Polyoxometalates Act as Anti-breast Cancer Drugs via Mitophagy-induced Apoptosis

C Yao, Z Zhao, T Tan, J Yan, Z Chen, J Xiong… - Current Medical …, 2024 - Springer
Abstract Objective Lindqvist-type polyoxometalates (POMs) exhibit potential antitumor
activities. This study aimed to examine the effects of Lindqvist-type POMs against breast …

Polyoxometalate–Polymer Hybrid Materials

L Ruiz-Rubio, I Moreno, JL Vilas-Vilela - Polyoxometalates, 2022 - taylorfrancis.com
The great variety of different structures and compositions of both polyoxometalates (POMs)
and polymers eases that the hybrid materials formed from them could be used in a diverse …