[HTML][HTML] Adverse cardiovascular effects of long-term exposure to diethyl phthalate in the rat aorta

M Mariana, M Lorigo, J Feiteiro, M Castelo-Branco… - Chemosphere, 2023 - Elsevier
Phthalates are classified as priority environmental pollutants, since they are ubiquitous in
the environment, have endocrine disrupting properties and can contribute to impaired …

[HTML][HTML] Cardioprotective effect of 2-methoxy phenol derivatives against oxidative stress-induced vascular complications: an integrated in vitro, in silico, and in vivo …

MT Aqeel, N Rahman, A Khan, MT Khan… - Biomedicine & …, 2023 - Elsevier
Background Oxidative stress and inflammation play crucial roles in macro/microvascular
complications. Phenolic compounds and their derivatives show promise as therapeutic …

Bergenin ameliorates diabetic nephropathy in C57BL/6 J mice by TLR4/MyD88/NF-κB signalling pathway regulation

Y Quan, P Su, C Shangguan, H Hao, L Yue… - Toxicology and Applied …, 2023 - Elsevier
Bergenin (BG) is a polyphenolic substance which has therapeutic potential in the treatment
of diabetic nephropathy (DN), a common complication of type II diabetes. However, the …

7-Hydroxy Frullanolide Ameliorates Isoproterenol-Induced Myocardial Injury through Modification of iNOS and Nrf2 Genes

S Ullah, T Ahmad, M Ikram, HM Rasheed, MI Khan… - Biomedicines, 2023 - mdpi.com
Myocardial infarction (MI) is the principal cause of premature death. Protecting myocardium
from ischemia is the main focus of intense research. 7-hydroxy frullanolide (7-HF) is a potent …

Bergenin ameliorates the progression of atherosclerosis by inhibiting oxidative stress, inflammation, and monocytes adhesion in human umbilical vein endothelial …

L Liang, W Yang - Molecular & Cellular Toxicology, 2024 - Springer
Background Bergenin is a type of polyphenol derived from various medicinal plants and has
multiple biological functions, including antioxidant, anti-cancerous, and anti-inflammatory …