Development of prefrontal cortex
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
Transient cortical circuits match spontaneous and sensory-driven activity during development
BACKGROUND During early mammalian brain development, transient neurons and circuits
form the scaffold for the development of neuronal networks. In the immature cerebral cortex …
form the scaffold for the development of neuronal networks. In the immature cerebral cortex …
[HTML][HTML] Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Genetic perturbations of cortical development can lead to neurodevelopmental disease,
including autism spectrum disorder (ASD). To identify genomic regions crucial to …
including autism spectrum disorder (ASD). To identify genomic regions crucial to …
[HTML][HTML] Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution
Human brain development is underpinned by cellular and molecular reconfigurations
continuing into the third decade of life. To reveal cell dynamics orchestrating neural …
continuing into the third decade of life. To reveal cell dynamics orchestrating neural …
Prefrontal cortex development in health and disease: lessons from rodents and humans
M Chini, IL Hanganu-Opatz - Trends in neurosciences, 2021 - cell.com
The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
Spatially resolved epigenomic profiling of single cells in complex tissues
The recent development of spatial omics methods has enabled single-cell profiling of the
transcriptome and 3D genome organization with high spatial resolution. Expanding the …
transcriptome and 3D genome organization with high spatial resolution. Expanding the …
Early diagnostics and early intervention in neurodevelopmental disorders—age-dependent challenges and opportunities
M Hadders-Algra - Journal of clinical medicine, 2021 - mdpi.com
This review discusses early diagnostics and early intervention in developmental disorders in
the light of brain development. The best instruments for early detection of cerebral palsy …
the light of brain development. The best instruments for early detection of cerebral palsy …
[图书][B] Volpe's Neurology of the Newborn
JJ Volpe, TE Inder, BT Darras, LS de Vries… - 2017 - books.google.com
A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …
Advancing models of neural development with biomaterials
Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …
LIF signaling regulates outer radial glial to interneuron fate during human cortical development
MG Andrews, C Siebert, L Wang, ML White, J Ross… - Cell stem cell, 2023 - cell.com
Radial glial (RG) development is essential for cerebral cortex growth and organization. In
humans, the outer radial glia (oRG) subtype is expanded and gives rise to diverse neurons …
humans, the outer radial glia (oRG) subtype is expanded and gives rise to diverse neurons …