Exploiting the Macrophage Production of IL-12 in Improvement of Vaccine Development against Toxoplasma gondii and Neospora caninum Infections
Toxoplasmosis and neosporosis are major protozoan diseases of global distribution.
Toxoplasma gondii is the cause of toxoplasmosis, which affects almost all warm-blooded …
Toxoplasma gondii is the cause of toxoplasmosis, which affects almost all warm-blooded …
Microglia in neuropathology caused by protozoan parasites
K Figarella, H Wolburg, O Garaschuk… - Biological …, 2020 - Wiley Online Library
Involvement of the central nervous system (CNS) is the most severe consequence of some
parasitic infections. Protozoal infections comprise a group of diseases that together affect …
parasitic infections. Protozoal infections comprise a group of diseases that together affect …
Thioredoxin reductase from Toxoplasma gondii: an essential virulence effector with antioxidant function
J Xue, W Jiang, Y Chen, F Gong, M Wang… - The FASEB …, 2017 - Wiley Online Library
Thioredoxin reductase (TR) can help pathogens resist oxidative‐burst injury from host
immune cells by maintaining a thioredoxin‐reduction state during NADPH consumption. TR …
immune cells by maintaining a thioredoxin‐reduction state during NADPH consumption. TR …
Immunization with Toxoplasma gondii peroxiredoxin 1 induces protective immunity against toxoplasmosis in mice
To develop a vaccine against Toxoplasma gondii, a vaccine antigen with immune-
stimulating activity is required. In the present study, we investigated the immunogenicity and …
stimulating activity is required. In the present study, we investigated the immunogenicity and …
Neospora GRA6 possesses immune-stimulating activity and confers efficient protection against Neospora caninum infection in mice
RM Fereig, N Shimoda, HH Abdelbaky, Y Kuroda… - Veterinary …, 2019 - Elsevier
Vaccination has the potential to be the most cost-effective control measure for reducing the
economic burden of neosporosis in cattle. In this study, the immune-stimulatory effect of …
economic burden of neosporosis in cattle. In this study, the immune-stimulatory effect of …
Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle
Neospora caninum is one of the main causes of transmissible abortion in cattle. Intraspecific
variations in virulence have been widely shown among N. caninum isolates. However, the …
variations in virulence have been widely shown among N. caninum isolates. However, the …
Involvement of Toll-like receptor 2 in the cerebral immune response and behavioral changes caused by latent Toxoplasma infection in mice
F Ihara, S Tanaka, RM Fereig, M Nishimura… - PLoS …, 2019 - journals.plos.org
Subacute and chronic infections with the intracellular protozoan parasite Toxoplasma gondii
are associated with an increased risk of psychiatric diseases like schizophrenia. However …
are associated with an increased risk of psychiatric diseases like schizophrenia. However …
Protective efficacy of recombinant Toxoplasma gondii dense granule protein 15 against toxoplasmosis in C57BL/6 mice
T Hasan, N Shimoda, S Nakamura, BA Fox, DJ Bzik… - Vaccine, 2024 - Elsevier
Toxoplasma gondii is a pervasive protozoan parasite that is responsible for significant
zoonoses. A wide array of vaccines using different effector molecules of T. gondii have been …
zoonoses. A wide array of vaccines using different effector molecules of T. gondii have been …
[PDF][PDF] Acute toxoplasmosis and antioxidant levels in the liver, kidney and brain of rats
SA Turkoglu, K Yaman, H Orallar, C Camsari… - Annals of …, 2018 - bibliotekanauki.pl
Toxoplasma gondii is a common protozoan parasite which causes toxoplasmosis
worldwide. There are limited treatment options against T. gondii infection. Once transmitted …
worldwide. There are limited treatment options against T. gondii infection. Once transmitted …
Evaluation of Immunodiagnostic Performances of Neospora caninum Peroxiredoxin 2 (NcPrx2), Microneme 4 (NcMIC4), and Surface Antigen 1 (NcSAG1) …
R Udonsom, P Adisakwattana, S Popruk, O Reamtong… - Animals, 2024 - mdpi.com
Simple Summary Bovine neosporosis is a widespread and economically impactful disease
affecting the dairy and meat industries globally. With no effective drug or vaccine available …
affecting the dairy and meat industries globally. With no effective drug or vaccine available …