[HTML][HTML] Ion channels in the heart
Optimal cardiac function depends on proper timing of excitation and contraction in various
regions of the heart, as well as on appropriate heart rate. This is accomplished via …
regions of the heart, as well as on appropriate heart rate. This is accomplished via …
Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?
PG Meregalli, AAM Wilde, HL Tan - Cardiovascular research, 2005 - academic.oup.com
After its recognition as a distinct clinical entity, Brugada syndrome is increasingly recognized
worldwide as an important cause of sudden cardiac death. Brugada syndrome exhibits …
worldwide as an important cause of sudden cardiac death. Brugada syndrome exhibits …
Electrical substrate elimination in 135 consecutive patients with Brugada syndrome
C Pappone, J Brugada, G Vicedomini… - Circulation …, 2017 - Am Heart Assoc
Background—There is emerging evidence that localization and elimination of abnormal
electric activity in the epicardial right ventricular outflow tract may be beneficial in patients …
electric activity in the epicardial right ventricular outflow tract may be beneficial in patients …
Brugada syndrome phenotype elimination by epicardial substrate ablation
J Brugada, C Pappone, A Berruezo… - Circulation …, 2015 - Am Heart Assoc
Background—Whether Brugada syndrome (BrS) depends on functional epicardial
substrates, which may be definitively eliminated by radiofrequency ablation, remains …
substrates, which may be definitively eliminated by radiofrequency ablation, remains …
Fragmented QRS as a marker of conduction abnormality and a predictor of prognosis of Brugada syndrome
H Morita, KF Kusano, D Miura, S Nagase… - Circulation, 2008 - Am Heart Assoc
Background—Conduction abnormalities serve as a substrate for ventricular fibrillation (VF)
in patients with Brugada syndrome (BS). Signal-averaged electrograms can detect late …
in patients with Brugada syndrome (BS). Signal-averaged electrograms can detect late …
Outcome after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: a multicenter study
F Sacher, V Probst, Y Iesaka, P Jacon, J Laborderie… - Circulation, 2006 - Am Heart Assoc
Background—Brugada syndrome is an arrhythmogenic disease characterized by an
increased risk of sudden cardiac death (SCD) by ventricular fibrillation. At present, an …
increased risk of sudden cardiac death (SCD) by ventricular fibrillation. At present, an …
Atrial fibrillation in patients with Brugada syndrome: relationships of gene mutation, electrophysiology, and clinical backgrounds
KF Kusano, M Taniyama, K Nakamura, D Miura… - Journal of the American …, 2008 - jacc.org
Objectives: The goal of our work was to examine the relationships of atrial fibrillation (AF)
with genetic, clinical, and electrophysiological backgrounds in Brugada syndrome (BrS) …
with genetic, clinical, and electrophysiological backgrounds in Brugada syndrome (BrS) …
Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data
M Paul, J Gerss, E Schulze-Bahr, T Wichter… - European heart …, 2007 - academic.oup.com
Aims Brugada syndrome (BS) is an ion channelopathy with the risk of sudden cardiac death.
The role of programmed ventricular stimulation (PVS) in risk stratification has been …
The role of programmed ventricular stimulation (PVS) in risk stratification has been …
Delay in right ventricular activation contributes to Brugada syndrome
R Tukkie, P Sogaard, J Vleugels, IKLM De Groot… - Circulation, 2004 - Am Heart Assoc
Background—Although Brugada syndrome revolves around reduced net depolarizing force,
the electrophysiological mechanisms of its defining features (right precordial ST-segment …
the electrophysiological mechanisms of its defining features (right precordial ST-segment …
JCS/JHRS 2022 guideline on diagnosis and risk assessment of arrhythmia
B Takase, T Ikeda, W Shimizu, H Abe, T Aiba… - Circulation …, 2023 - jstage.jst.go.jp
Sinus node dysfunction may be either transient (reversible/physiological) due to the
involvement of the autonomic nervous system or pharmaceuticals, or chronic due to …
involvement of the autonomic nervous system or pharmaceuticals, or chronic due to …