Beyond the three-chamber test: toward a multimodal and objective assessment of social behavior in rodents

R Jabarin, S Netser, S Wagner - Molecular Autism, 2022 - Springer
Main In recent years, substantial advances in social neuroscience have been realized,
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

In vivo multi-day calcium imaging of CA1 hippocampus in freely moving rats reveals a high preponderance of place cells with consistent place fields

HS Wirtshafter, JF Disterhoft - Journal of Neuroscience, 2022 - Soc Neuroscience
Calcium imaging using GCaMP indicators and miniature microscopes has been used to
image cellular populations during long timescales and in different task phases, as well as to …

Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline

CJ Padilla, ME Harrigan, H Harris, JM Schwab… - Geroscience, 2021 - Springer
Pathological age-related loss of skeletal muscle strength and mass contribute to impaired
physical function in older adults. Factors that promote the development of these conditions …

In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats

X Zheng, EB Arias, NR Qi, TL Saunders, GD Cartee - PLoS One, 2020 - journals.plos.org
The Rab GTPase activating protein known as Akt substrate of 160 kDa (AS160 or TBC1D4)
regulates insulin-stimulated glucose uptake in skeletal muscle, the heart, and white adipose …

Transcranial direct current stimulation for balance and gait in repetitive mild traumatic brain injury in rats

G Park, JH Suh, SJ Han - BMC neuroscience, 2021 - Springer
Background Balance impairment and lack of postural orientation are serious problems in
patients with repetitive mild traumatic brain injury (mTBI). Objective To investigate whether …

Species-dependent extracranial manifestations of a brain seeking breast cancer cell line

V De Meulenaere, S Neyt, B Vandeghinste, P Mollet… - PLoS …, 2018 - journals.plos.org
Purpose Metastatic brain tumors pose a severe problem in the treatment of patients with
breast carcinoma. Preclinical models have been shown to play an important role in …

On the basis of sex: male vs. female rat adenosine A1/A2A receptor affinity

HD Janse van Rensburg, G Terre'Blanche… - BMC Research …, 2023 - Springer
Objective To ensure reproducibility in biomedical research, the biological variable sex must
be reported; yet a reason for using male (instead of female) rodents is seldom given. In our …

[PDF][PDF] On the basis of sex: male vs. female rat adenosine A

HDJ van Rensburg, G Terre'Blanche… - 2023 - bmcresnotes.biomedcentral.com
Objective To ensure reproducibility in biomedical research, the biological variable sex must
be reported; yet a reason for using male (instead of female) rodents is seldom given. In our …

Intestinal iron absorption is appropriately modulated to match physiological demand for iron in wild-type and iron-loaded Hamp (hepcidin) knockout rats during acute …

SRL Flores, S Nelson, RR Woloshun, X Wang, JH Ha… - Plos one, 2021 - journals.plos.org
Mucosal damage, barrier breach, inflammation, and iron-deficiency anemia (IDA) typify
ulcerative colitis (UC) in humans. The anemia in UC appears to mainly relate to systemic …