ABC transporters are essential for cellular physiology. Humans have 48 ABC genes
organized into seven distinct families. Of these genes, 44 (in five distinct families) encode for …

ATP-binding cassette (ABC) transporters belong to one of the largest families of membrane
proteins, and are present in almost all living organisms from eubacteria to mammals. They …

Human ABC transporter ABCD1 transports very long-chain fatty acids from cytosol to
peroxisome for β-oxidation, dysfunction of which usually causes the X-linked …

Peroxisomes contribute to several crucial metabolic processes such as β-oxidation of fatty
acids, biosynthesis of ether phospholipids and metabolism of reactive oxygen species …

Peroxisomes are membrane-bound organelles involved in many metabolic pathways and
essential for human health. They harbor a large number of enzymes involved in the different …

ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of
conserved proteins from bacteria to mammals. In humans, three members of this family are …

ABCD3 is one of three ATP-binding cassette (ABC) transporters present in the peroxisomal
membrane catalyzing ATP-dependent transport of substrates for metabolic pathways …

Abstract X‐linked adrenoleukodystrophy (X‐ALD) is caused by mutations in the ABCD1
gene encoding the peroxisomal ABC transporter adrenoleukodystrophy protein (ALDP). X …

The gene mutated in X-linked adrenoleukodystrophy (X-ALD) codes for the HsABCD1
protein, also named ALDP, which is a member of the superfamily of ATP-binding cassette …

Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …