Low‐Molecular Weight Compounds that Extend the Chronological Lifespan of Yeasts, Saccharomyces cerevisiae, and Schizosaccharomyces pombe

H Ohtsuka, T Shimasaki, H Aiba - Advanced Biology, 2024 - Wiley Online Library
Yeast is an excellent model organism for research for regulating aging and lifespan, and the
studies have made many contributions to date, including identifying various factors and …

A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

G Urbonaite, JTH Lee, P Liu, GE Parada… - Communications …, 2021 - nature.com
Stochastic gene expression leads to inherent variability in expression outcomes even in
isogenic single-celled organisms grown in the same environment. The Drop-Seq technology …

Integrated metabolomics and transcriptomics reveal glyphosate based‐herbicide induced reproductive toxicity through disturbing energy and nucleotide metabolism …

L Qi, Y Li, Y Dong, S Ma, G Li - Environmental Toxicology, 2023 - Wiley Online Library
Glyphosate is a widely used herbicide that has deleterious effects on animal reproduction.
However, details regarding the systematic mechanisms of glyphosate‐induced reproductive …

A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

U Guste, LJT Hang, P Liu, GE Parada… - Communications …, 2021 - search.proquest.com
Stochastic gene expression leads to inherent variability in expression outcomes even in
isogenic single-celled organisms grown in the same environment. The Drop-Seq technology …

Isonicotinamide extends yeast chronological lifespan through a mechanism that diminishes nucleotides

A Kalita, EE Hesles, LN Power, D Wang, PK Singh… - bioRxiv, 2021 - biorxiv.org
Chronological lifespan (CLS) of budding yeast, Saccharomyces cerevisiae, is a commonly
utilized model for cellular aging of non-dividing cells such as neurons. CLS is strongly …

Tracking Single Cell Lineages in Saccharomyces cerevisiae

G Urbonaite - 2021 - search.proquest.com
The ability to measure the number of gene-specific mRNA molecules in individual
mammalian cells has transformed the transcriptomics field. Among the key technologies …