Commercial promotion of unsupported therapeutic uses of stem cells is a global problem
that has proven resistant to regulatory efforts. Here, we suggest a coordinated approach at …

Genome editing is a powerful new tool for making precise alterations to an organism's
genetic material. Recent scientific advances have made genome editing more efficient …

STUDY QUESTION What are the reasons for or against the future clinical application of
germline genome modification (GGM)? SUMMARY ANSWER A total of 169 reasons were …

We assessed the extent to which the publication of clinical trial results of innovative cell-
based interventions reflects International Society for Stem Cell Research best practice …

Rogues and Regulation of Germline Editing Calling for a moratorium on germline editing
won't stop rogue actors. Instead, an “ecosystem” approach to regulation might minimize …

As governments around the world struggle to govern a multitude of emerging technologies,
they often seek to harmonize their regulatory approaches. But there are at least 10 different …

We are living in a golden age of medicine in which the availability of prenatal diagnosis, fetal
therapy, and gene therapy/editing make it theoretically possible to repair almost any defect …

Regenerative medicine therapies, underpinned by the core principles of rejuvenation,
regeneration and replacement, are shifting the paradigm in healthcare from symptomatic …

Human gene editing, particularly using the new CRISPR/Cas9 technology, will greatly
increase the capability to make precise changes to human genomes. Human gene editing …

A central problem for the international governance of heritable germline gene editing is that
there are important differences in attitudes and values as well as ethical and health care …