Mechanisms of DNA Damage Response in Mammalian Oocytes

F Sun, P Sutovsky, AL Patterson… - … Mammalian Oocyte Quality …, 2024 - Springer
DNA damage poses a significant challenge to all eukaryotic cells, leading to mutagenesis,
genome instability and senescence. In somatic cells, the failure to repair damaged DNA can …

[引用][C] Oocytes, Metabolism and DNA Repair: Elucidating the Interplay in a Translational Ageing Model

H NEWMAN - 2024 - bridges.monash.edu
This thesis evaluated key factors in the decline of mouse and human egg quality with age;
metabolism and DNA repair capacity. It identified unique energy levels and differences in …