IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Gestational diabetes mellitus and preeclampsia: correlation and influencing factors

Y Yang, N Wu - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are common pregnancy
complications with similar risk factors and pathophysiological changes. Evidence from …

Pre-eclampsia part 1: current understanding of its pathophysiology

T Chaiworapongsa, P Chaemsaithong, L Yeo… - Nature Reviews …, 2014 - nature.com
Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …

Pre-eclampsia: its pathogenesis and pathophysiolgy: review articles

P Gathiram, J Moodley - Cardiovascular journal of Africa, 2016 - journals.co.za
Pre-eclampsia is a pregnancy-specific disorder that has a worldwide prevalence of 5-8%. It
is one of the main causes of maternal and perinatal morbidity and mortality globally and …

[HTML][HTML] Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia

DS Boeldt, IM Bird - The Journal of endocrinology, 2017 - ncbi.nlm.nih.gov
Maternal vascular adaptation to pregnancy is critically important in order to expand the
capacity for blood flow through the uteroplacental unit to meet the needs of the developing …

From pregnancy to preeclampsia: a key role for estrogens

N Berkane, P Liere, JP Oudinet, A Hertig… - Endocrine …, 2017 - academic.oup.com
Preeclampsia (PE) results in placental dysfunction and is one of the primary causes of
maternal and fetal mortality and morbidity. During pregnancy, estrogen is produced primarily …

Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies

A Umapathy, LW Chamley, JL James - Angiogenesis, 2020 - Springer
A branched vascular network is crucial to placental development and is dependent on
factors such as vascular endothelial growth factor (VEGF), placental growth factor (PlGF) …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia

S Tong, J Tu'uhevaha, R Hastie, F Brownfoot… - American journal of …, 2022 - Elsevier
There has been increasing research momentum to identify new therapeutic agents for the
prevention or treatment of preeclampsia, drugs that can affect the underlying disease …

Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta

CA Labarrere, HL DiCarlo, E Bammerlin… - American journal of …, 2017 - Elsevier
Background Failure of physiologic transformation of spiral arteries has been reported in
preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact …