Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

Early-Life Origins of Chronic Obstructive Pulmonary Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Airway remodeling is generally quite broadly defined as any change in composition,
distribution, thickness, mass or volume and/or number of structural components observed in …

Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …

Severe asthma in children is rare, accounting for only a small proportion of childhood
asthma. After addressing modifiable factors such as adherence to treatment, comorbidities …

Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

BETWEEN BEDSIDE AND BENCH differentiation of naive T lymphocytes toward TH2 cells,
which produce cytokines such as interleukin-4 (IL-4), IL-5, IL-9 and IL-13 (ref. 2). Allergic …

There is poor agreement on definitions of different phenotypes of preschool wheezing
disorders. The present Task Force proposes to use the terms episodic (viral) wheeze to …

Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …