Schistosomiasis morbidity hotspots: roles of the human host, the parasite and their interface in the development of severe morbidity

PA Mawa, J Kincaid-Smith, EM Tukahebwa… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis is the second most important human parasitic disease in terms of
socioeconomic impact, causing great morbidity and mortality, predominantly across the …

[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

Myco-synthesized molluscicidal and larvicidal selenium nanoparticles: A new strategy to control Biomphalaria alexandrina snails and larvae of Schistosoma mansoni …

MY Morad, H El-Sayed, AA Elhenawy, SM Korany… - Journal of Fungi, 2022 - mdpi.com
Schistosomiasis is a tropical disease with socioeconomic problems. The goal of this study
was to determine the influence of myco-synthesized nano-selenium (SeNPs) as a …

Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy

LE Coffeng, WA Stolk, SJ de Vlas - Nature Communications, 2024 - nature.com
Control of soil-transmitted helminths relies heavily on regular large-scale deworming of high-
risk groups (eg, children) with benzimidazole derivatives. Although drug resistance has not …

[HTML][HTML] Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

DJ Berger, T Crellen, PHL Lamberton, F Allan… - Nature …, 2021 - nature.com
Control and elimination of the parasitic disease schistosomiasis relies on mass
administration of praziquantel. Whilst these programmes reduce infection prevalence and …

A review of the genetic determinants of praziquantel resistance in Schistosoma mansoni: Is praziquantel and intestinal schistosomiasis a perfect match?

S Summers, T Bhattacharyya, F Allan… - Frontiers in Tropical …, 2022 - frontiersin.org
Schistosomiasis is a neglected tropical disease (NTD) caused by parasitic trematodes
belonging to the Schistosoma genus. The mainstay of schistosomiasis control is the delivery …

Population genetics of African Schistosoma species

O Rey, BL Webster, T Huyse, D Rollinson… - Infection, Genetics and …, 2021 - Elsevier
Blood flukes within the genus Schistosoma (schistosomes) are responsible for the major
disease, schistosomiasis, in tropical and sub-tropical areas. This disease is predominantly …

The impact of mass drug administration on Schistosoma haematobium infection: what is required to achieve morbidity control and elimination?

K Kura, RJ Hardwick, JE Truscott, J Toor… - Parasites & …, 2020 - Springer
Background Schistosomiasis remains an endemic parasitic disease causing much morbidity
and, in some cases, mortality. The World Health Organization (WHO) has outlined strategies …

Genomic analysis of a parasite invasion: Colonization of the Americas by the blood fluke Schistosoma mansoni

RN Platt, W Le Clec'h, FD Chevalier… - Molecular …, 2022 - Wiley Online Library
Schistosoma mansoni, a snail‐borne, blood fluke that infects humans, was introduced into
the Americas from Africa during the Trans‐Atlantic slave trade. As this parasite shows strong …

Reconciling Egg- and Antigen-Based Estimates of Schistosoma mansoni Clearance and Reinfection: A Modeling Study

J Clark, A Moses, A Nankasi, CL Faust… - Clinical Infectious …, 2022 - academic.oup.com
Background Despite decades of interventions, 240 million people have schistosomiasis.
Infections cannot be directly observed, and egg-based Kato-Katz thick smears lack …