The roles of IL-1 family cytokines in the pathogenesis of systemic sclerosis
D Xu, R Mu, X Wei - Frontiers in immunology, 2019 - frontiersin.org
The IL-1 family consists of 11 cytokines, 7 ligands with agonist activity (IL-1α, IL-1β, IL-18, IL-
33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor …
33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor …
Interleukin-1 and systemic sclerosis: getting to the heart of cardiac involvement
Systemic sclerosis (SSc) is rare, severe connective tissue disease characterized by
endothelial and vascular damage, immune activation, and resulting in inflammation and …
endothelial and vascular damage, immune activation, and resulting in inflammation and …
Genetic factors and systemic sclerosis
G Murdaca, M Contatore, R Gulli, P Mandich… - Autoimmunity …, 2016 - Elsevier
Systemic sclerosis (SSc) is a rare connective tissue disease of unknown etiology
characterized by chronic inflammation and fibrosis of the skin, vascular abnormalities, and …
characterized by chronic inflammation and fibrosis of the skin, vascular abnormalities, and …
Targeting TLRs and the inflammasome in systemic sclerosis
J Henderson, S Bhattacharyya, J Varga… - Pharmacology & …, 2018 - Elsevier
Systemic sclerosis (SSc) is an idiopathic autoimmune disease characterised by
inflammation, vascular problems, cytokine dysregulation and ultimately fibrosis, which …
inflammation, vascular problems, cytokine dysregulation and ultimately fibrosis, which …
Cardiovascular, respiratory, and total mortality ascribed to PM10 and PM2. 5 exposure in Isfahan, Iran
A Abdolahnejad, N Jafari, A Mohammadi… - Journal of education …, 2017 - journals.lww.com
BACKGROUND: Elderly people often suffer from sleep disorders. Chamomile due to the
many health benefits such as sedation may be effective in improving sleep quality in elderly …
many health benefits such as sedation may be effective in improving sleep quality in elderly …
Association of C3953T transition in interleukin 1β gene with idiopathic male infertility in an Iranian population
In this study we investigate the association of C3953T transition single nucleotide
polymorphism in the fifth exon of the interleukin 1β gene with idiopathic male infertility. In a …
polymorphism in the fifth exon of the interleukin 1β gene with idiopathic male infertility. In a …
The immunogenetics of systemic sclerosis
Systemic sclerosis (SSc) is a rare disease with a prevalence ranging from 7 to 700 cases per
million. Like with most autoimmune diseases, both environmental and genetic factors are …
million. Like with most autoimmune diseases, both environmental and genetic factors are …
Relationships between IL-1β, TNF-α genetic polymorphisms and HBV infection: A meta-analytical study
Y Wei, Z Zhao, Z Wang, K Zhang, Z Tang, C Tao - Gene, 2021 - Elsevier
Background IL-1β and TNF-α have been demonstrated as pro-inflammatory cytokines to
participate in the innate immune response and suppression of HBV infection. However, the …
participate in the innate immune response and suppression of HBV infection. However, the …
Evaluation of ITGB2 (CD18) and SELL (CD62L) genes expression and methylation of ITGB2 promoter region in patients with systemic sclerosis
N Dashti, M Mahmoudi, F Gharibdoost… - Rheumatology …, 2018 - Springer
Systemic sclerosis (SSc), an autoimmune disease of connective tissue, is characterized by
inflammation, fibrosis, and vessel endothelial damage. Products of Integrin subunit beta 2 …
inflammation, fibrosis, and vessel endothelial damage. Products of Integrin subunit beta 2 …
Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis
M Mahmoudi, F Fallahian, S Sobhani, S Ghoroghi… - Clinical …, 2017 - Springer
Genetic factors have a great role in the pathogenesis of autoimmune diseases by
cooperating with environmental stimuli. Killer immunoglobulin-like receptors (KIRs) are cell …
cooperating with environmental stimuli. Killer immunoglobulin-like receptors (KIRs) are cell …