Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis

MA Kelshiker, H Seligman, JP Howard… - European heart …, 2022 - academic.oup.com
Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-
cause mortality and major adverse cardiovascular events (MACE) across a broad range of …

Ischemia and no obstructive coronary artery disease (INOCA) developing evidence-based therapies and research agenda for the next decade

CN Bairey Merz, CJ Pepine, MN Walsh, JL Fleg… - Circulation, 2017 - Am Heart Assoc
The Cardiovascular Disease in Women Committee of the American College of Cardiology,
in conjunction with interested parties (from the National Heart, Lung, and Blood Institute …

Clinical quantification of myocardial blood flow using PET: joint position paper of the SNMMI cardiovascular council and the ASNC

VL Murthy, TM Bateman, RS Beanlands, DS Berman… - 2018 - Springer
Radionuclide myocardial perfusion imaging (MPI) is among the most commonly performed
diagnostic tests in cardiology. Although the diagnostic and prognostic applications of …

EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging

R Sciagrà, M Lubberink, F Hyafil, A Saraste… - European Journal of …, 2021 - Springer
The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been
growing during the last years, because scanners are becoming widely available and …

Improved cardiac risk assessment with noninvasive measures of coronary flow reserve

VL Murthy, M Naya, CR Foster, J Hainer, M Gaber… - Circulation, 2011 - Am Heart Assoc
Background—Impaired vasodilator function is an early manifestation of coronary artery
disease and may precede angiographic stenosis. It is unknown whether noninvasive …

Association between coronary vascular dysfunction and cardiac mortality in patients with and without diabetes mellitus

VL Murthy, M Naya, CR Foster, M Gaber, J Hainer… - Circulation, 2012 - Am Heart Assoc
Background—Diabetes mellitus increases the risk of adverse cardiac outcomes and is
considered a coronary artery disease (CAD) equivalent. We examined whether coronary …

Impaired myocardial flow reserve on rubidium-82 positron emission tomography imaging predicts adverse outcomes in patients assessed for myocardial ischemia

MC Ziadi, RA Dekemp, KA Williams, A Guo… - Journal of the American …, 2011 - jacc.org
Objectives: We evaluated the prognostic value of myocardial flow reserve (MFR) using
rubidium-82 (82Rb) positron emission tomography (PET) in patients assessed for ischemia …

Coronary microvascular dysfunction: clinical considerations and noninvasive diagnosis

TH Schindler, V Dilsizian - Cardiovascular imaging, 2020 - jacc.org
Chest pain in patients without obstructive coronary artery disease has been realized as a
frequent problem encountered in clinical practice. Invasive flow investigations have …

Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health

TH Schindler, HR Schelbert, A Quercioli… - JACC: Cardiovascular …, 2010 - jacc.org
Positron emission tomography (PET) myocardial perfusion imaging in concert with tracer-
kinetic modeling affords the assessment of regional myocardial blood flow (MBF) of the left …

Preserved coronary flow reserve effectively excludes high-risk coronary artery disease on angiography

M Naya, VL Murthy, VR Taqueti, CR Foster… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Myocardial perfusion imaging has limited sensitivity for the detection of high-risk coronary
artery disease (CAD). We tested the hypothesis that a normal coronary flow reserve (CFR) …