HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia
S Zhang, L Hu, J Jiang, H Li, Q Wu, K Ooi… - Journal of …, 2020 - Springer
Background Microglial mediated neuroinflammation in the rostral ventrolateral medulla
(RVLM) plays roles in the etiology of stress-induced hypertension (SIH). It was reported that …
(RVLM) plays roles in the etiology of stress-induced hypertension (SIH). It was reported that …
Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies
H Kai, M Kai, H Niiyama, N Okina, M Sasaki… - Hypertension …, 2021 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) protects against organ damage in
hypertension and cardiovascular diseases by counter regulating the renin-angiotensin …
hypertension and cardiovascular diseases by counter regulating the renin-angiotensin …
Maternal protein malnutrition induced‐hypertension: New evidence about the autonomic and respiratory dysfunctions and epigenetic mechanisms
JL de Brito Alves, JH Costa‐Silva - Clinical and Experimental …, 2018 - Wiley Online Library
Maternal protein malnutrition during the critical stages of development (pregnancy, lactation
and first infancy) can lead to adult hypertension. Studies have shown that renal and …
and first infancy) can lead to adult hypertension. Studies have shown that renal and …
SARS-CoV-2 downregulation of ACE2 and pleiotropic effects of ACEIs/ARBs
MM Ciulla - Hypertension Research, 2020 - nature.com
Following the concerns triggered by the emergence of SARS-CoV-2 and the COVID-19
pandemic with its high mortality rate, mainly in older people with one or more cardiovascular …
pandemic with its high mortality rate, mainly in older people with one or more cardiovascular …
Microglia-derived NLRP3 activation mediates the pressor effect of prorenin in the rostral ventrolateral medulla of stress-induced hypertensive rats
Increased microglial activation and neuroinflammation within autonomic brain regions such
as the rostral ventrolateral medulla (RVLM) have been implicated in stress-induced …
as the rostral ventrolateral medulla (RVLM) have been implicated in stress-induced …
Loss of angiotensin-converting enzyme 2 promotes growth of gallbladder cancer
H Zong, B Yin, H Zhou, D Cai, B Ma, Y Xiang - Tumor Biology, 2015 - Springer
The aim of this study is to investigate the role of angiotensin-converting enzyme 2 (ACE2) in
gallbladder cancer (GBC) and the therapeutic potential of angiotensin receptor blocker in …
gallbladder cancer (GBC) and the therapeutic potential of angiotensin receptor blocker in …
[HTML][HTML] Role of the renin-angiotensin system, renal sympathetic nerve system, and oxidative stress in chronic foot shock-induced hypertension in rats
T Dong, JW Chen, LL Tian, LH Wang… - … journal of biological …, 2015 - ncbi.nlm.nih.gov
Objective: The renin-angiotensin system (RAS) and renal sympathetic nerve system (RSNS)
are involved in the development of hypertension. The present study is designed to explore …
are involved in the development of hypertension. The present study is designed to explore …
History of vascular reactivity models and their involvement in hypertension pathogenesis
Hypertension is a silent and multifactorial disease. Over two centuries ago, the first device to
record blood pressure was developed, making it possible to determine normotension and to …
record blood pressure was developed, making it possible to determine normotension and to …
Studies of salt and stress sensitivity on arterial pressure in renin-b deficient mice
Excessive sodium intake is known to increase the risk for hypertension, heart disease, and
stroke. Individuals who are more susceptible to the effects of high salt are at higher risk for …
stroke. Individuals who are more susceptible to the effects of high salt are at higher risk for …
[HTML][HTML] The effect of candesartan on chronic stress induced imbalance of glucose homeostasis
MJ Chen, YJ Wei, XX Dong, JY Liu, QY Chen… - Biomedicine & …, 2020 - Elsevier
Objective To explore whether chronic stress induces imbalance of glucose homeostasis,
and to investigate the possible involvement of the renin-angiotensin system (RAS). Methods …
and to investigate the possible involvement of the renin-angiotensin system (RAS). Methods …