The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …

Aryl halides are an indispensably important class of compounds owing to their role as
precursors in the synthesis of organometallic reagents and nucleophilic substitution …

An unexpected rhodium-catalyzed regioselective C–H chlorination of 7-azaindoles was
developed using 1, 2-dichloroethane (DCE) as a chlorinating agent and 7-azaindole as the …

The palladium-catalyzed ortho-selective chlorination of N-quinolinylbenzamide derivatives
with hydrochloric acid was achieved under anodic oxidation conditions. The use of 5, 7 …

A novel and efficient copper-catalyzed amination of N-aryl imines is described. This one-pot,
multicomponent reaction, in which imine acts as a directing group by chelating to the metal …

Copper (II)-catalyzed oxidative cross-coupling of anilines, primary alkyl amines, and sodium
azide is described in the presence of TBHP at moderate temperature. This one-pot …

The initial discovery and establishment of a family of novel iridium catalysts possessing N‐
heterocyclic carbene units alongside bulky phosphine ligands allowed selected substrates …

The first examples of selective ortho-directed C–H activation with unprotected 2-
aryltetrazoles are described. A new base-assisted protocol for iridium (I) hydrogen isotope …

The ubiquity of carbon halogen bonds in the structural core of numerous biomolecules and
pharmaceuticals along with their role as synthetic precursors in various organic reactions …

A palladium-catalyzed, ortho-selective C–H halogenation methodology is reported herein.
The highlight of the work is the highly selective C (sp2)–H functionalization of benzyl nitriles …