Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment

S Huang, H Lu, J Chen, C Jiang, G Jiang… - Journal of Materials …, 2024 - pubs.rsc.org
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global
health hazard. Currently, traditional treatments for renal fibrosis are difficult to meet clinical …

Application of nanotechnology in the treatment of glomerulonephritis: current status and future perspectives

HQ Zhan, X Zhang, XL Chen, L Cheng… - Journal of …, 2024 - Springer
Glomerulonephritis (GN) is the most common cause of end-stage renal failure worldwide; in
most cases, it cannot be cured and can only delay the progression of the disease. At …

Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review

S Nag, O Mitra, G Tripathi, S Samanta… - Immunity …, 2023 - Wiley Online Library
Background Autoimmune diseases (AD) are severe pathophysiological ailments that are
stimulated by an exaggerated immunogenic response towards self‐antigens, which can …

Targeted drug delivery strategy: a bridge to the therapy of diabetic kidney disease

X Chen, W Dai, H Li, Z Yan, Z Liu, L He - Drug Delivery, 2023 - Taylor & Francis
Diabetic kidney disease (DKD) is the main complication in diabetes mellitus (DM) and the
main cause of end-stage kidney disease worldwide. However, sodium glucose cotransporter …

On-demand Opto-Laser activatable nanoSilver ThermoGel for treatment of full-thickness diabetic wound in a mouse model

B Pawar, S Otavi, A Singh, S Kaur, RK Tekade - Biomaterials Advances, 2024 - Elsevier
Patients suffering from diabetes mellitus are prone to develop diabetic wounds that are non-
treatable with conventional therapies. Hence, there is an urgent need of hour to develop the …

Dendronized polymeric biomaterial for loading, stabilization, and targeted cytosolic delivery of microRNA in cancer cells

V Tambe, S Patel, A Shard, SK Behera… - ACS Applied Bio …, 2022 - ACS Publications
MicroRNAs (miRNAs) are small non-coding RNAs involved in the fine-tuning of gene
regulation. Anti-miRNA is a promising RNA-interference (RNAi) agent that potently regulates …

Podocyte senescence: from molecular mechanisms to therapeutics

Q Zhao, Y Huang, N Fu, C Cui, X Peng, H Kang… - Renal …, 2024 - Taylor & Francis
As an important component of the glomerular filtration membrane, the state of the podocytes
is closely related to kidney function, they are also key cells involved in aging and play a …