Zinc is a crucial trace element in the human body, playing a role in various physiological
processes such as oxidative stress, neurotransmission, protein synthesis, and DNA repair …

Heavy metals, including lead (Pb), cadmium (Cd), arsenic (As), cobalt (Co), copper (Cu),
manganese (Mn), zinc (Zn), and others, have a significant impact on the development and …

Amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease and similar
neurodegenerative disorders take their toll on patients, caregivers and society. A common …

TDP-43 proteinopathy is implicated in the neurodegenerative diseases, ALS and FTLD-TDP.
Metal ion dyshomeostasis is observed in neurodegenerative diseases including ALS …

As misfolding and aggregation of the RNA/DNA-binding protein, TDP-43, are linked to
devastating TDP-43 proteinopathies like amyotrophic lateral sclerosis (ALS), distinction of …

In recent years, peptides have received increased interest in pharmaceutical, food,
cosmetics, and various other fields. The high potency, specificity, and good safety profile are …

Abstract mRNA and protein clump—or condense—in response to cellular stress across the
tree of eukaryotic life. Yet, despite decades of inquiry and its universal evolutionary …

S100A1 is a member of the S100 family of small ubiquitous Ca2+-binding proteins, which
participates in the regulation of cell differentiation, motility, and survival. It exists as homo-or …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by
progressive loss in function of motor neurons. Elevated levels of biologically important metal …

Liquid-liquid phase separation (LLPS) is emerging as a common principle for organizing
biomolecular condensates, including membrane-less organelles (MLOs), which are critical …