Molecular diagnostics are revolutionising the clinical practice of infectious disease. Their
effects will be significant in acute-care settings where timely and accurate diagnostic tools …

The human immunodeficiency virus–type 1 (HIV-1) envelope glycoproteins interact with
receptors on the target cell and mediate virus entry by fusing the viral and cell membranes …

The hypothesis that quiescent CD4+ T lymphocytes carrying proviral DNA provide a
reservoir for human immunodeficiency virus–type 1 (HIV-1) in patients on highly active …

A new mathematical model was used to analyze a detailed set of human immunodeficiency
virus-type 1 (HIV-1) viral load data collected from five infected individuals after the …

Background and Methods Maternal-infant transmission is the primary means by which
young children become infected with human immunodeficiency virus type 1 (HIV). We …

Abstract Treatment of infected patients with ABT-538, an inhibitor of the protease of human
immuno-deficiency virus type 1 (HIV-1), causes plasma HIV-1 levels to decrease …

Combination therapy for HIV-1 infection can reduce plasma virus to undetectable levels,
indicating that prolonged treatment might eradicate the infection. However, HIV-1 can persist …

The capacity of HIV-1 to establish latent infection of CD4+ T cells may allow viral persistence
despite immune responses and antiretroviral therapy. Measurements of infectious virus1, 2 …

Virologic and immunologic studies were performed on five patients presenting with primary
human immunodeficiency virus type 1 (HIV-1) infection. CD8+ cytotoxic T lymphocyte (CTL) …

Abstract Analysis of changes in viral load after initiation of treatment with potent antiretroviral
agents has provided substantial insight into the dynamics of human immunodeficiency virus …