Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

Optimisation of drug delivery through human skin is important in modern therapy. This
review considers drug–vehicle interactions (drug or prodrug selection, chemical potential …

Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

The protective function of human skin imposes physicochemical limitations to the type of
permeant that can traverse the barrier. For a drug to be delivered passively via the skin it …

Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the
application of high voltage pulses. Its application to the skin has been shown to increase …

The Handbook of Pharmaceutical Controlled Release Technology reviews the design,
fabrication, methodology, administration, and classifications of various drug delivery …

Electrical pulses that cause the transmembrane voltage of fluid lipid bilayer membranes to
reach at least U/sub m//spl ap/0.2 V, usually 0.5-1 V, are hypothesized to create primary …

Transdermal delivery of pharmacologically active agents has been extensively studied for
the past 40 years. Despite the strong efforts, currently, only about 40 products are in market …

Cell electropermeabilization (also termed cell electroporation) is nowadays a routine
technique used in biochemical and pharmacological studies for the in vitro introduction of …

Transdermal drug delivery has many potential advantages, but the skin's poorly-permeable
stratum corneum blocks delivery of most drugs at therapeutic levels. Short high-voltage …