Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of
therapy resistance is a hot topic in epigenetics. As one of the most common RNA …

Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant
cancers exhibit complex molecular mechanisms to hit back therapy under pharmacological …

RNA modification has recently become a significant process of gene regulation, and the
methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification …

The Warburg effect is a hallmark of cancer that refers to the preference of cancer cells to
metabolize glucose anaerobically rather than aerobically,. This results in substantial …

Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

Abstract N6-methyladenosine (m6A) RNA modification is the most common and conserved
epigenetic modification in mRNA and has been shown to play important roles in cancer …

Oxaliplatin is a widely applied anti-cancer drug in clinics for colorectal cancer (CRC)
treatment. Nonetheless, the treatment efficacy is always limited by the acquisition of …

Aims Chemoresistance remains a major challenge in gastric cancer (GC). Chromodomain
helicase DNA-binding protein 4 (CHD4) mediated chromatin remodeling plays critical roles …

Gastric cancer is the fourth most frequent cancer and has a high death rate. Immunotherapy
represented by PD-1 has brought hope for the treatment of advanced gastric cancer …

Simple Summary N6-methyladenosine (m6A) is the most abundant internal modification in
eukaryotic mRNA and plays a crucial role in the occurrence and development of diseases …