New insights into iNKT cells and their roles in liver diseases
X Gu, Q Chu, X Ma, J Wang, C Chen, J Guan… - Frontiers in …, 2022 - frontiersin.org
Natural killer T cells (NKTs) are an important part of the immune system. Since their
discovery in the 1990s, researchers have gained deeper insights into the physiology and …
discovery in the 1990s, researchers have gained deeper insights into the physiology and …
Leishmaniasis: immune cells crosstalk in macrophage polarization
FS Almeida, SER Vanderley, FC Comberlang… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …
Type I natural killer T cells as key regulators of the immune response to infectious diseases
The immune system must work in an orchestrated way to achieve an optimal response upon
detection of antigens. The cells comprising the immune response are traditionally divided …
detection of antigens. The cells comprising the immune response are traditionally divided …
Exploring the paradox of defense between host and Leishmania parasite
Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …
healthcare sector. The primary causative agents of the disease comprise diverse …
[HTML][HTML] Functional aspects of T cell diversity in visceral leishmaniasis
Co-ordination between innate and adaptive immunity is a foremost crucial immunological
interactions. The interaction is beneficial for the survival of the host against infectious agent …
interactions. The interaction is beneficial for the survival of the host against infectious agent …
[HTML][HTML] Chemokines in Leishmaniasis: Map of cell movements highlights the landscape of infection and pathogenesis
FF de Araújo, MF Costa-Silva, AAS Pereira, FD Rêgo… - Cytokine, 2021 - Elsevier
Pathogen interactions with the host immune response components are critical for
establishing protective immunity and pathological responses against Leishmania parasites …
establishing protective immunity and pathological responses against Leishmania parasites …
Foxp3+ Tregs from Langerhans cell histiocytosis lesions co-express CD56 and have a definitively regulatory capacity
J Mitchell, J Kelly, E Kvedaraite… - Clinical …, 2020 - Elsevier
Langerhans cell histiocytosis (LCH) lesions contain myeloid lineage 'LCH'cells. Regulatory
T cells (Tregs) are also enriched within lesions, although their role in LCH pathogenesis is …
T cells (Tregs) are also enriched within lesions, although their role in LCH pathogenesis is …
C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model
YH Liu, L Zhu, ZW Zhang, TT Liu, QY Cheng… - Journal of Translational …, 2023 - Springer
Background Previous studies have demonstrated that natural killer (NK) cells migrated into
the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus …
the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus …
Visceral Leishmaniasis in Immunocompetent Hosts in Brescia: A Case Series and Analysis of Cytokine Cascade
A Mulè, V Crosato, DB Kuhns, L Lorenzi, C Chirico… - Microorganisms, 2024 - mdpi.com
Visceral leishmaniasis (VL) is a parasitic zoonosis caused by Leishmania spp. that usually
manifests itself in immunocompromised subjects. It is a rare and neglected disease, and it is …
manifests itself in immunocompromised subjects. It is a rare and neglected disease, and it is …
Chemokines Signature and T Cell Dynamics in Leishmaniasis: Molecular insight and therapeutic application
Leishmaniasis, caused by obligate intracellular Leishmania parasites, poses a significant
global 19 health burden. The control of Leishmania infection relies on an effective T cell …
global 19 health burden. The control of Leishmania infection relies on an effective T cell …