Drug carrier for photodynamic cancer therapy

TA Debele, S Peng, HC Tsai - International journal of molecular sciences, 2015 - mdpi.com
Photodynamic therapy (PDT) is a non-invasive combinatorial therapeutic modality using
light, photosensitizer (PS), and oxygen used for the treatment of cancer and other diseases …

A review of toxicity studies on graphene-based nanomaterials in laboratory animals

M Ema, M Gamo, K Honda - Regulatory Toxicology and Pharmacology, 2017 - Elsevier
We summarized the findings of toxicity studies on graphene-based nanomaterials (GNMs) in
laboratory mammals. The inhalation of graphene (GP) and graphene oxide (GO) induced …

Nanoparticles as a solution for eliminating the risk of mycotoxins

P Horky, S Skalickova, D Baholet, J Skladanka - Nanomaterials, 2018 - mdpi.com
Mycotoxins are toxic secondary metabolites produced by certain filamentous fungi. The
occurrence of mycotoxins in food and feed causes negative health impacts on both humans …

Graphene‐based biomaterials for bone regenerative engineering: a comprehensive review of the field and considerations regarding biocompatibility and …

L Daneshmandi, M Barajaa… - Advanced …, 2021 - Wiley Online Library
Graphene and its derivatives have continued to garner worldwide interest due to their
unique characteristics. Having expanded into biomedical applications, there have been …

Graphene oxide touches blood: In vivo interactions of bio-coronated 2D materials

V Palmieri, G Perini, M De Spirito, M Papi - Nanoscale Horizons, 2019 - pubs.rsc.org
Graphene oxide is the hot topic in biomedical and pharmaceutical research of the current
decade. However, its complex interactions with human blood components complicate the …

Mitochondria-targeted graphene for advanced cancer therapeutics

TA Tabish, RJ Narayan - Acta Biomaterialia, 2021 - Elsevier
There have been numerous efforts to develop targeted therapies for treating cancer. The
non-specificity of'classical'cytotoxic chemotherapy drugs and drug resistance remain major …

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide

S Bengtson, KB Knudsen, ZO Kyjovska, T Berthing… - PloS one, 2017 - journals.plos.org
We investigated toxicity of 2–3 layered> 1 μm sized graphene oxide (GO) and reduced
graphene oxide (rGO) in mice following single intratracheal exposure with respect to …

Use of a pro-fibrogenic mechanism-based predictive toxicological approach for tiered testing and decision analysis of carbonaceous nanomaterials

X Wang, MC Duch, N Mansukhani, Z Ji, YP Liao… - ACS …, 2015 - ACS Publications
Engineered carbonaceous nanomaterials (ECNs), including single-wall carbon nanotubes
(SWCNTs), multiwall carbon nanotubes (MWCNTs), graphene, and graphene oxide (GO) …

Catalytic nanographene oxide with hemin for enhanced photodynamic therapy

A Sahu, K Min, J Jeon, HS Yang, G Tae - Journal of Controlled Release, 2020 - Elsevier
Hypoxia is a hallmark of many malignant solid tumors. The inadequate oxygen
concentration in the hypoxic regions of a solid tumor impedes the efficiency of photodynamic …

The effects of extensive glomerular filtration of thin graphene oxide sheets on kidney physiology

DA Jasim, S Murphy, L Newman, A Mironov, E Prestat… - ACS …, 2016 - ACS Publications
Understanding how two-dimensional (2D) nanomaterials interact with the biological milieu is
fundamental for their development toward biomedical applications. When thin …