Shaping the brain vasculature in development and disease in the single-cell era
T Wälchli, J Bisschop, P Carmeliet, G Zadeh… - Nature Reviews …, 2023 - nature.com
The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning
P Vempati, AS Popel, F Mac Gabhann - Cytokine & growth factor reviews, 2014 - Elsevier
The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …
neovascularization in numerous tissues under physiological and pathological conditions …
Intussusceptive angiogenesis: expansion and remodeling of microvascular networks
SJ Mentzer, MA Konerding - Angiogenesis, 2014 - Springer
Intussusceptive angiogenesis is a dynamic intravascular process capable of dramatically
modifying the structure of the microcirculation. The distinctive structural feature of …
modifying the structure of the microcirculation. The distinctive structural feature of …
Tumor angiogenesis revisited: regulators and clinical implications
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
Intussusceptive angiogenesis: a biologically relevant form of angiogenesis
W De Spiegelaere, C Casteleyn… - Journal of vascular …, 2012 - karger.com
Angiogenesis, ie the development and growth of blood vessels, is a major topic of research
as it plays an important role in normal development and in various pathologies. Recent …
as it plays an important role in normal development and in various pathologies. Recent …
Intussusceptive angiogenesis and its role in vascular morphogenesis, patterning, and remodeling
AN Makanya, R Hlushchuk, VG Djonov - Angiogenesis, 2009 - Springer
New blood vessels arise initially as blood islands in the process known as vasculogenesis
or as new capillary segments produced through angiogenesis. Angiogenesis itself …
or as new capillary segments produced through angiogenesis. Angiogenesis itself …
Understanding vascular development
RS Udan, JC Culver… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
The vasculature of an organism has the daunting task of connecting all the organ systems to
nourish tissue and sustain life. This complex network of vessels and associated cells must …
nourish tissue and sustain life. This complex network of vessels and associated cells must …
EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF
E Groppa, S Brkic, A Uccelli, G Wirth… - EMBO …, 2018 - embopress.org
Vascular endothelial growth factor (VEGF) is the master regulator of angiogenesis, whose
best‐understood mechanism is sprouting. However, therapeutic VEGF delivery to ischemic …
best‐understood mechanism is sprouting. However, therapeutic VEGF delivery to ischemic …
Spatiotemporal control over growth factor signaling for therapeutic neovascularization
L Cao, DJ Mooney - Advanced drug delivery reviews, 2007 - Elsevier
Many of the qualitative roles of growth factors involved in neovascularization have been
delineated, but it is unclear yet from an engineering perspective how to use these factors as …
delineated, but it is unclear yet from an engineering perspective how to use these factors as …
The roles and role-players in thyroid cancer angiogenesis
Thyroid cancer is the most prevalent endocrine cancer worldwide. Angiogenesis, the
formation of new blood vessels, plays a pivotal role in the development and progression of …
formation of new blood vessels, plays a pivotal role in the development and progression of …