Correct operation of neuronal networks depends on the interplay between synaptic
excitation and inhibition processes leading to a dynamic state termed balanced network. In …

Persistent inward currents (PICs) are responsible for amplifying motoneuronal synaptic
inputs and contribute to generating normal motoneuron activation. Delta-F (ΔF) is a well …

During development of the spinal cord, a precise interaction occurs between descending
projections and sensory afferents, with spinal networks that lead to expression of …

Human umbilical cord mesenchymal stem cells (hUC-MSCs) support revascularization,
inhibition of inflammation, regulation of apoptosis, and promotion of the release of beneficial …

Background Persons with acute low back pain (LBP) have a good prognosis for regaining
function, while pain often persists. Neurobiological and psychosocial factors are recognized …

Changes in motor and sensory properties occur either side of spinal cord lesion sites from
lower vertebrates to humans. We have previously examined these changes in the lamprey, a …

Postural limb reflexes (PLRs) are an essential component of postural corrections.
Spinalization leads to disappearance of postural functions (including PLRs). After …

Human umbilical cord mesenchymal stem cells (hUC-MSCs) support revascularization,
inhibition of inflammation, regulation of apop tosis, and promotion of the release of beneficial …

Windup is a form of multisecond temporal summation in which identical stimuli, delivered
seconds apart, trigger increasingly strong neuronal responses. L-type Ca2+ channels have …

We have known for many years that the spinal cord can generate some basic locomotor
outputs under specific experimental conditions without any input from the brain or the …