Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …

A number of effective maintenance medication options exist for bipolar disorder (BD) and
these are regarded as the foundation of long-term treatment in BD. However, nonadherence …

The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …

Background The neurotrophic hypothesis postulates that mood disorders such as bipolar
disorder (BD) are associated with a lower expression of brain-derived neurotrophic factor …

Objective The authors sought to assess the efficacy of functional remediation, a novel
intervention program, on functional improvement in a sample of euthymic patients with …

Objective We aimed to review clinical features and biological underpinnings related to
neuroprogression in bipolar disorder (BD). Also, we discussed areas of controversy and …

Objective We discuss the rationale behind staging systems described specifically for bipolar
disorders. Current applications, future directions and research gaps in clinical staging …

BackgroundLittle is known about whether treatment in a specialised out-patient mood
disorder clinic improves long-term prognosis for patients discharged from initial psychiatric …

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

This Review discusses crucial areas related to the identification, clinical presentation,
course, and therapeutic management of bipolar disorder, a major psychiatric illness. Bipolar …