Background: Identifying a poor degree of awareness of cognitive decline (ACD) could
represent an early indicator of Alzheimer's disease (AD). Objectives:(1) to understand …

Functional neuroimaging techniques (ie single photon emission computed tomography,
positron emission tomography, and functional magnetic resonance imaging) have been …

Objective To assess the frequency of biologically defined Alzheimer disease (AD) in relation
to age, sex, APOE ε4, and clinical diagnosis in a prospective cohort study evaluated with …

Background Mitochondrial electron transport chain abnormalities have been reported in
postmortem pathological specimens of Alzheimer's disease (AD). However, it remains …

APOEε4 is the most well-established genetic risk factor for sporadic Alzheimer's disease and
is associated with cerebral amyloid-β. However, the association between APOEε4 and tau …

Objective Unawareness, or anosognosia, of memory deficits is a challenging manifestation
of Alzheimer's disease (AD) that adversely affects a patient's safety and decision‐making …

Objective Unawareness of a deficit, anosognosia, can occur for visual or motor deficits and
lends insight into awareness itself; however, lesions associated with anosognosia occur in …

Objective To determine the associations between amyloid-PET, tau-PET, and atrophy with
the behavioral/dysexecutive presentation of Alzheimer disease (AD), how these differ from …

Awareness of one's own cognitive processes (metacognition) or of one's own illness or
deficits (anosognosia) can be impaired in people with Alzheimer's disease (AD). The neural …

While anosognosia is often present in Alzheimer's disease, the degree of awareness of
cognitive difficulties in the earlier stages, such as Mild Cognitive Impairment (MCI), is less …