WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of
AD is considered to be multifactorial as only a negligible percentage of cases have a familial …

The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

Abstract Glycogen synthase kinase-3 (GSK3) is now recognized as a key component of a
surprisingly large number of cellular processes and diseases. Several mechanisms play a …

Abstract Glycogen synthase kinase-3 (GSK-3) is an unusual protein-serine kinase in that it is
primarily regulated by inhibition and lies downstream of multiple cell signaling pathways …

Summary The Disrupted in Schizophrenia 1 (DISC1) gene is disrupted by a balanced
chromosomal translocation (1; 11)(q42; q14. 3) in a Scottish family with a high incidence of …

Deciphering what governs inflammation and its effects on tissues is vital for understanding
many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes …

Özet Zinc is essential in the regulation of a variety of physiological and biochemical events
in the organism. It plays a critical role in maintaining the cell membrane integrity, protein …

Neurodegenerative diseases are among the most challenging diseases with poorly known
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …

Abstract Glycogen synthase kinase-3 (GSK3) was initially identified more than two decades
ago as an enzyme involved in the control of glycogen metabolism. In recent years it has …