Epithelial–mesenchymal transition (EMT) is a process whereby epithelial cells are
transcriptionally reprogrammed, resulting in decreased adhesion and enhanced migration …

The renaissance of the laboratory rabbit as a reproductive model for human health is closely
related to the growing evidence of periconceptional metabolic programming and its …

BACKGROUND Pluripotent cells are generated by embryonic divisions that occur shortly
after fertilization. These cells are transformed into the recognizable outline of an organism …

Background: During gastrulation, an embryo acquires the three primordial germ layers that
will give rise to all of the tissues in the body. In amniote embryos, this process occurs via an …

Body axis elongation and segmentation are major morphogenetic events that take place
concomitantly during vertebrate embryonic development. Establishment of the final body …

Gastrulation is a stage in embryo development where three germ layers arise to dictate the
human body plan. In vitro models of gastrulation have been demonstrated by treating …

In the animal kingdom, gastrulation, the process by which the primary germ layers are
formed involves a dramatic transformation in the topology of the cells that give rise to all of …

The emergence of the bilateral embryonic body axis from a symmetrical egg has been a
long-standing question in developmental biology. Historical and modern experiments point …

bromoacetamide (BAcAm), a new class of disinfection by-products (DBPs), is widely
detected in drinking water across the world. Reports of the high cytogenetic toxicity of …

Background: Mouse embryos are cup shaped, but most nonrodent eutherian embryos are
disk shaped. Extraembryonic ectoderm (ExEc), which may have essential roles in anterior …