[HTML][HTML] Pulsed electromagnetic fields in bone healing: molecular pathways and clinical applications

L Caliogna, M Medetti, V Bina, AM Brancato… - International Journal of …, 2021 - mdpi.com
In this article, we provide an extensive review of the recent literature of the signaling
pathways modulated by Pulsed Electromagnetic Fields (PEMFs) and PEMFs clinical …

[HTML][HTML] Bone healing gone wrong: pathological fracture healing and non-unions—overview of basic and clinical aspects and systematic review of risk factors

D Saul, MM Menger, S Ehnert, AK Nüssler, T Histing… - Bioengineering, 2023 - mdpi.com
Bone healing is a multifarious process involving mesenchymal stem cells, osteoprogenitor
cells, macrophages, osteoblasts and-clasts, and chondrocytes to restore the osseous tissue …

Underlying signaling pathways and therapeutic applications of pulsed electromagnetic fields in bone repair

J Yuan, F Xin, W Jiang - Cellular Physiology and Biochemistry, 2018 - karger.com
Pulsed electromagnetic field (PEMF) stimulation, as a prospective, noninvasive, and safe
physical therapy strategy to accelerate bone repair has received tremendous attention in …

[HTML][HTML] Extremely low frequency pulsed electromagnetic fields cause antioxidative defense mechanisms in human osteoblasts via induction of •O2 and H2O2

S Ehnert, AK Fentz, A Schreiner, J Birk, B Wilbrand… - Scientific reports, 2017 - nature.com
Recently, we identified a specific extremely low-frequency pulsed electromagnetic field (ELF-
PEMF) that supports human osteoblast (hOBs) function in an ERK1/2-dependent manner …

Physical stimulations for bone and cartilage regeneration

X Huang, R Das, A Patel, T Duc Nguyen - Regenerative engineering and …, 2018 - Springer
A wide range of techniques and methods are actively invented by clinicians and scientists
who are dedicated to the field of musculoskeletal tissue regeneration. Biological, chemical …

[HTML][HTML] Translational insights into extremely low frequency pulsed electromagnetic fields (ELF-PEMFs) for bone regeneration after trauma and orthopedic surgery

S Ehnert, S Schröter, RH Aspera-Werz, W Eisler… - Journal of clinical …, 2019 - mdpi.com
The finding that alterations in electrical potential play an important role in the mechanical
stimulation of the bone provoked hype that noninvasive extremely low frequency pulsed …

[HTML][HTML] Intermittent exposure to a 16 Hz extremely low frequency pulsed electromagnetic field promotes osteogenesis in vitro through activating Piezo 1-induced …

Y Chen, BJ Braun, MM Menger, M Ronniger… - Journal of Functional …, 2023 - mdpi.com
Exposure to extremely low frequency pulsed electromagnetic fields (ELF-PEMF) is
supposed to simulate local EMF generated during mechanical stimulation of bone and may …

Effects of pulsed electromagnetic fields on postmenopausal osteoporosis

S Zhu, H He, C Zhang, H Wang, C Gao… - …, 2017 - Wiley Online Library
Postmenopausal osteoporosis (PMOP) is considered to be a well‐defined subject that has
caused high morbidity and mortality. In elderly women diagnosed with PMOP, low bone …

[HTML][HTML] Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair

AM Hollenberg, A Huber, CO Smith, RA Eliseev - Scientific reports, 2021 - nature.com
Bone fracture is a growing public health burden and there is a clinical need for non-invasive
therapies to aid in the fracture healing process. Previous studies have demonstrated the …

[HTML][HTML] Modulation of macrophage activity by pulsed electromagnetic fields in the context of fracture healing

Y Chen, MM Menger, BJ Braun, S Schweizer… - Bioengineering, 2021 - mdpi.com
Delayed fracture healing and fracture non-unions impose an enormous burden on
individuals and society. Successful healing requires tight communication between immune …