Progesterone is essential for the maintenance of pregnancy, and progesterone deficiency is
associated with miscarriage. The subject of whether progesterone supplementation in early …

The aim of this systematic review and meta-analysis was to conduct a comprehensive
assessment of the evidence on the efficacy and safety of oral dydrogesterone versus …

The physical and psychological effect of miscarriage is commonly underappreciated. The
journey from diagnosis of miscarriage, through clinical management, to supportive aftercare …

STUDY QUESTION Is oral dydrogesterone 30 mg daily non-inferior to 8% micronized
vaginal progesterone (MVP) gel 90 mg daily for luteal phase support in IVF? SUMMARY …

The pharmacological and physiological profiles of progestogens used for luteal phase
support during assisted reproductive technology are likely to be important in guiding clinical …

STUDY QUESTION Does the addition of oral dydrogesterone to vaginal progesterone as
luteal phase support improve pregnancy outcomes during frozen embryo transfer (FET) …

No data support the suggestion that first-trimester dydrogesterone use increases the risk of
foetal abnormalities; however, two low-quality retrospective studies (one retracted by the …

Natural progesterone (P4) has a unique pharmacodynamic activity and safety profile
compared to the synthetic progestins. As a result, a class effect does not exist for both P4 …

Progestational agents are often prescribed to prevent pregnancy loss. Progestogens affect
implantation, cytokine balance, natural killer cell activity, arachidonic acid release and …

Purpose Dydrogesterone (DYG) has been demonstrated to be an alternative progestin in the
progestin-primed ovarian stimulation (PPOS) protocol with comparable oocyte retrieval and …