Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives

JCT Chio, KJ Xu, P Popovich, S David… - Experimental …, 2021 - Elsevier
Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …

[HTML][HTML] Economic impact of traumatic spinal cord injuries in the United States

CH Merritt, MA Taylor, CJ Yelton… - Neuroimmunology and …, 2019 - ncbi.nlm.nih.gov
Individuals having sustained traumatic spinal cord injury (TSCI) in the United States are
living longer as compared to historical trends, thanks to an ever-evolving understanding of …

[HTML][HTML] Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice

C Wang, L Zhang, JDLC Ndong… - Journal of …, 2019 - Springer
Purpose Spinal cord injury (SCI) often results in significant and catastrophic dysfunction and
disability and imposes a huge economic burden on society. This study aimed to determine …

Glutathione-modified macrophage-derived cell membranes encapsulated metformin nanogels for the treatment of spinal cord injury

Q Yu, X Jiang, X Liu, W Shen, X Mei, H Tian, C Wu - Biomaterials advances, 2022 - Elsevier
Spinal cord injury (SCI) causes a range of pathological responses, including oxidative
stress, inflammation and apoptosis. In SCI treatment, whether an effective drug preparation …

[HTML][HTML] Global neurosurgery in the context of global public health practice–a literature review of case studies

VR Veerappan, PJ Gabriel, NA Shlobin, K Marks… - World Neurosurgery, 2022 - Elsevier
Neurosurgical conditions are a substantial contributor to surgical burden worldwide, with low-
and middle-income countries carrying a disproportionately large part. Policy initiatives such …

Cost-effectiveness of operating on traumatic spinal injuries in low-middle income countries: a preliminary report from a major East African referral center

NL Lessing, SL Zuckerman, A Lazaro… - Global Spine …, 2022 - journals.sagepub.com
Study Design: Retrospective cost-effectiveness analysis. Objectives: While the incidence of
traumatic spine injury (TSI) is high in low-middle income countries (LMICs), surgery is rarely …

[HTML][HTML] Traumatic spinal cord injury among patients admitted to the spine unit in a tertiary care centre

S Gautam, B Rijal, LK Sharma - JNMA: Journal of the Nepal …, 2023 - ncbi.nlm.nih.gov
Methods: A descriptive cross-sectional study was done in a tertiary care centre among
patients admitted to the Spine Unit from 1 January 2022 to 31 December 2022 after …

Traumatic thoracic and lumbar spine injury in adult population presenting to a Tertiary Care Hospital

B Parajuli, S Kayastha, J Thapa, D Shrestha - 2022 - 103.69.126.140
Background: Epidemiology of traumatic thoracolumbar spine injury is a less explored
subject in developing/underdeveloped countries. The number of available studies in Nepal …

Severity and neurosurgical management of patients with traumatic spinal fractures in Saudi Arabia: a cross sectional study

KH Aldosari, YM Aldhfyan, MH Karrar… - Pan African Medical …, 2019 - ajol.info
Introduction: road traffic accidents (RTAs) are the most frequent cause of traumatic spinal
injuries (TSIs), which account for up to 33.6% of all spinal fractures. The Kingdom of Saudi …

[HTML][HTML] Evaluation of disc degeneration adjacent to AOspine A fractures: pre-and post-operative MRI analysis

L Marie-Hardy, N Barut, HS Ali, M Khalifé… - SICOT-J, 2020 - ncbi.nlm.nih.gov
Introduction: The management of type A thoracolumbar fractures varies from conservative
treatment to multiple level fusion. Indeed, although Magerl defined the type A fracture as a …