[HTML][HTML] The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

BDNF and synaptic plasticity, cognitive function, and dysfunction

B Lu, G Nagappan, Y Lu - Neurotrophic factors, 2014 - Springer
Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …

[HTML][HTML] What is memory? The present state of the engram

M Poo, M Pignatelli, TJ Ryan, S Tonegawa… - BMC biology, 2016 - Springer
The mechanism of memory remains one of the great unsolved problems of biology.
Grappling with the question more than a hundred years ago, the German zoologist Richard …

[HTML][HTML] Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

N Singewald, C Schmuckermair, N Whittle… - Pharmacology & …, 2015 - Elsevier
Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

Histone acetylation: molecular mnemonics on the chromatin

J Gräff, LH Tsai - Nature Reviews Neuroscience, 2013 - nature.com
Long-lasting memories require specific gene expression programmes that are, in part,
orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in …

Epigenetics and the biological definition of gene× environment interactions

MJ Meaney - Child development, 2010 - Wiley Online Library
Variations in phenotype reflect the influence of environmental conditions during
development on cellular functions, including that of the genome. The recent integration of …

Lasting epigenetic influence of early-life adversity on the BDNF gene

TL Roth, FD Lubin, AJ Funk, JD Sweatt - Biological psychiatry, 2009 - Elsevier
BACKGROUND: Childhood maltreatment and early trauma leave lasting imprints on neural
mechanisms of cognition and emotion. With a rat model of infant maltreatment by a …

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

S Srivastav, S Neupane, S Bhurtel, N Katila… - The Journal of …, 2019 - Elsevier
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic …