This review discusses current understanding of the role that endogenous and exogenous
progenitor cells may have in the treatment of the diseased heart. In the last several years, a …

Stem cell transplantation has emerged as a potential modality in cardiovascular therapeutics
due to their inherent characteristics of self-renewal, unlimited capacity for proliferation and …

Cardiac tissue engineering is an emerging field. The suitability of engineered heart tissue
(EHT) for both in vitro and in vivo applications will depend on the degree of syncytoid tissue …

M. Zhang, D. Methot, V. Poppa, Y. Fujio, K. Walsh and CE Murry. Cardiomyocyte Grafting for
Cardiac Repair: Graft Cell Death and Anti-Death Strategies. Journal of Molecular and …

Background—Bone marrow–derived stem cells are under investigation as a treatment for
ischemic heart disease. Mesenchymal stem cells (MSCs) have been used preferentially in …

Background. A novel therapeutic option for the treatment of acute myocardial infarction
involves the use of mesenchymal stem cells (MSCs). The purpose of this study was to …

Engraftment of mesenchymal stem cells (MSCs) derived from adult bone marrow has been
proposed as a potential therapeutic approach for postinfarction left ventricular dysfunction …

Vascularization of engineered tissues in vitro and in vivo remains a key problem in
translation of engineered tissues to clinical practice. Growth factor signalling can be …

Background—Cellular cardiomyoplasty is a promising approach to improve postinfarcted
cardiac function. The differentiation pathways of engrafted mesenchymal progenitor cells …

Objective: The study evaluated the utility of transplanting bone marrow stromal cells in a
porcine myocardial infarction model. Methods: A myocardial infarction was created by …