Long-term normothermic machine preservation of partial livers: first experience with 21 human hemi-livers
Objective: The aim of this study was to maintain long-term full function and viability of partial
livers perfused ex situ for sufficient duration to enable ex situ treatment, repair, and …
livers perfused ex situ for sufficient duration to enable ex situ treatment, repair, and …
Bile formation in long-term ex situ perfused livers
Background Long-term ex situ liver perfusion may rescue injured grafts. Little is known about
bile flow during long-term perfusion. We report the development of a bile stimulation protocol …
bile flow during long-term perfusion. We report the development of a bile stimulation protocol …
Automated Insulin Delivery - Continuous Blood Glucose Control During Ex Situ Liver Perfusion
D Becker, D Eshmuminov, R Keller… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Objective: With the growing demand for livers in the field of transplantation, interest in
normothermic ex situ machine perfusion (NMP) has increased in recent years. This may …
normothermic ex situ machine perfusion (NMP) has increased in recent years. This may …
Sources and prevention of graft infection during long‐term ex situ liver perfusion
Introduction The use of normothermic liver machine perfusion to repair injured grafts ex situ
is an emerging topic of clinical importance. However, a major concern is the possibility of …
is an emerging topic of clinical importance. However, a major concern is the possibility of …
Observations and findings during the development of a subnormothermic/normothermic long‐term ex vivo liver perfusion machine
Background Ex situliver machine perfusion at subnormothermic/normothermic temperature
isincreasingly applied in the field of transplantation to store and evaluateorgans on the …
isincreasingly applied in the field of transplantation to store and evaluateorgans on the …
Virtual lobule models are the key for multiscale biomechanical and pharmacological modeling for the liver
H Ho, E Zhang - Frontiers in physiology, 2020 - frontiersin.org
The liver has a unique dual blood-supply system of hepatic arterial (HA) and portal venous
(PV) vasculatures, which are drained by a hepatic venous (HV) tree (Figure 1A). The blood …
(PV) vasculatures, which are drained by a hepatic venous (HV) tree (Figure 1A). The blood …
Synthesis of coagulation factors during long‐term ex situ liver perfusion
Robust viability assessment of grafts during normothermic liver perfusion is a prerequisite for
organ use. Coagulation parameters are used commonly for liver assessment in patients …
organ use. Coagulation parameters are used commonly for liver assessment in patients …
Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed
Long-term perfusion of liver grafts outside of the body may enable repair of poor-quality
livers that are currently declined for transplantation, mitigating the global shortage of donor …
livers that are currently declined for transplantation, mitigating the global shortage of donor …
Adaptive simulation of 3D thermometry maps for interventional MR-guided tumor ablation using Pennes' bioheat equation and isotherms
Minimally-invasive thermal ablation procedures have become clinically accepted treatment
options for tumors and metastases. Continuous and reliable monitoring of volumetric heat …
options for tumors and metastases. Continuous and reliable monitoring of volumetric heat …
Left renal vein graft and in situ hepatic perfusion in hepatectomy for complete tumor invasion of hepatic veins: hemodynamic optimization and surgical technique
Purpose Assessing hepatic vein reconstruction using a left renal vein graft and in situ
hypothermic liver perfusion in an extended liver resection. Methods Patients included in this …
hypothermic liver perfusion in an extended liver resection. Methods Patients included in this …