Traumatic optic neuropathy or other neurodegenerative diseases, including optic nerve
transection, glaucoma, and diabetic retinopathy, can lead to progressive and irreversible …

Understanding the consequences of individual transcriptome variation is fundamental to
deciphering human biology and disease. We implement a statistical framework to quantify …

Traumatic Brain Injury (TBI) is a major cause of disability and mortality, particularly among
the elderly, yet our mechanistic understanding of how age renders the post-traumatic brain …

Ocular disorders can significantly lower patients' quality of life and impose an economic
burden on families and society. However, for the majority of these diseases, their prevalence …

Inflammation plays an important role in the pathogenesis of diabetic retinopathy (DR). To
precisely define the inflammatory mediators, we examined the transcriptomic profile of …

Objective To reveal the core mechanism of berberine (BBR) in the treatment of diabetic
retinopathy (DR), by using Four-dimensional independent data acquisition (4D-DIA) …

Single-cell RNA sequencing (scRNA-seq) analysis have provided an unprecedented
resolution for the studies on diabetic retinopathy (DR). However, the early changes in the …

Diabetic retinopathy (DR) is a common consequence of diabetes mellitus and a primary
cause of visual impairment in middle-aged and elderly individuals. DR is susceptible to …

Diabetic nephropathy (DN) and diabetic retinopathy (DR), as microvascular complications of
diabetes mellitus, are currently the leading causes of end-stage renal disease (ESRD) and …

Over the past few decades, diabetes gradually has become one of the top non‐
communicable disorders, affecting 476.0 million in 2017 and is predicted to reach 570.9 …