[HTML][HTML] Artificial intelligence in retina

U Schmidt-Erfurth, A Sadeghipour, BS Gerendas… - Progress in retinal and …, 2018 - Elsevier
Major advances in diagnostic technologies are offering unprecedented insight into the
condition of the retina and beyond ocular disease. Digital images providing millions of …

[HTML][HTML] Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

A Subrizi, EM Del Amo, V Korzhikov-Vlakh… - Drug discovery today, 2019 - Elsevier
Highlights•Ocular drug delivery is a field in which regular ADME tools are not useful.•
Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly …

[HTML][HTML] Prediction of individual disease conversion in early AMD using artificial intelligence

U Schmidt-Erfurth, SM Waldstein… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: While millions of individuals show early age-related macular degeneration (AMD)
signs, yet have excellent vision, the risk of progression to advanced AMD with legal …

Association of retinal nerve fiber layer thinning with current and future cognitive decline: a study using optical coherence tomography

F Ko, ZA Muthy, J Gallacher, C Sudlow, G Rees… - JAMA …, 2018 - jamanetwork.com
Importance Identifing potential screening tests for future cognitive decline is a priority for
developing treatments for and the prevention of dementia. Objective To examine the …

[HTML][HTML] An open-source framework for end-to-end analysis of electronic health record data

L Heumos, P Ehmele, T Treis, J Upmeier zu Belzen… - Nature Medicine, 2024 - nature.com
With progressive digitalization of healthcare systems worldwide, large-scale collection of
electronic health records (EHRs) has become commonplace. However, an extensible …

Unsupervised identification of disease marker candidates in retinal OCT imaging data

P Seeböck, SM Waldstein, S Klimscha… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
The identification and quantification of markers in medical images is critical for diagnosis,
prognosis, and disease management. Supervised machine learning enables the detection …

Automated detection of glaucoma with interpretable machine learning using clinical data and multimodal retinal images

P Mehta, CA Petersen, JC Wen, MR Banitt… - American Journal of …, 2021 - Elsevier
Purpose To develop a multimodal model to automate glaucoma detection Design
Development of a machine-learning glaucoma detection model Methods We selected a …

Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank

SYL Chua, A Warwick, T Peto, K Balaskas… - British Journal of …, 2022 - bjo.bmj.com
Aim To examine the associations of air pollution with both self-reported age-related macular
degeneration (AMD), and in vivo measures of retinal sublayer thicknesses. Methods We …

[HTML][HTML] Atlas of human retinal pigment epithelium organelles significant for clinical imaging

A Pollreisz, M Neschi, KR Sloan… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: To quantify organelles impacting imaging in the cell body and intact apical
processes of human retinal pigment epithelium (RPE), including melanosomes, lipofuscin …

Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort

SYL Chua, G Lascaratos, D Atan… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Current methods to diagnose neurodegenerative diseases are
costly and invasive. Retinal neuroanatomy may be a biomarker for more neurodegenerative …