Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Emerging microfluidic disease models have amply demonstrated their value in many fields
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …

Shear stress, pressure, and flow rate are fluid dynamic parameters that can lead to changes
in the morphology, proliferation, function, and survival of many cell types and have a …

Fas ligand (FasL, CD178) is known to bind to its receptor (Fas, CD95) and mediate cellular
apoptosis to maintain immune homeostasis. Recently, it has been recognized that tumor …

Human microbiota communicates with its host by secreting signaling metabolites, enzymes,
or structural components. Its homeostasis strongly influences the modulation of human …

Vascular endothelial cells (ECs) respond to mechanical stimuli caused by blood flow to
maintain vascular homeostasis. Although the oxygen level in vascular microenvironment is …

Keratin biomaterials with high molecular weights were intensively investigated but few are
marketed due to complex methods of extraction and preparation and limited understanding …

Blood and lymphatic vessels are regulators of physiological processes, including
oxygenation and fluid transport. Both vessels are ubiquitous throughout the body and are …

Bacterial infections frequently occur within or near the vascular network as the vascular
network connects organ systems and is essential in delivering and removing blood …

The effects of helical flow in a blood vessel are investigated in a dynamic flow generator
using surface acoustic wave (SAW) in the microfluidic device. The SAW, generated by an …