Results We found that ALCDs are critical regions of the human genome that are located on
all human chromosomes, preferentially in intronic regions of the oncogenes and other …

FoundationOne® CDx (F1CDx) is a United States (US) Food and Drug Administration (FDA)-
approved companion diagnostic test to identify patients who may benefit from treatment in …

The most common primary malignant liver tumor of childhood, hepatoblastoma has
increased in incidence over the last 30 years, but little is still known about its pathogenesis …

Background & Aims Hepatoblastoma (HB) is the most frequent childhood liver cancer.
Patients with aggressive tumors have limited therapeutic options; therefore, a better …

Hepatoblastoma is a malignant tumor in the liver of children that generally occurs at the age
of 2–3 years. There have been ample evidence from the preclinical as well as clinical …

Hepatoblastoma (HB) is the most common form of primary liver malignancy found in
pediatric populations. HB is considered to be clonal and arises from hepatoblasts, or …

Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total
hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then …

Hepatoblastoma (HBL) is a pediatric liver cancer that affects children under the age of three.
Reduction of tumor suppressor proteins (TSPs) is commonly seen in liver cancer. However …

Hepatoblastoma (HB) is the predominant primary liver tumor in children. While the prognosis
is favorable when the tumor can be resected, the outcome is dismal for patients with …

Hepatoblastoma is the most common hepatic malignancy during childhood. However, little is
still known about the molecular mechanisms that govern the development of this disease …