Molecular mechanisms of asymmetric division in oocytes

SC Sun, NH Kim - Microscopy and microanalysis, 2013 - academic.oup.com
In contrast to symmetric division in mitosis, mammalian oocyte maturation is characterized
by asymmetric cell division that produces a large egg and a small polar body. The …

Bypassing Mendel's First Law: transmission ratio distortion in mammals

G Friocourt, A Perrin, PA Saunders… - International Journal of …, 2023 - mdpi.com
Mendel's law of segregation states that the two alleles at a diploid locus should be
transmitted equally to the progeny. A genetic segregation distortion, also referred to as …

[HTML][HTML] Transcriptome and proteome analysis of pregnancy and postpartum anoestrus ovaries in yak

Z Chen, J Wang, J Ma, S Li, S Huo, Y Yang… - Journal of Veterinary …, 2022 - ncbi.nlm.nih.gov
Background Domestic yaks are the most important livestock species on the Qinghai-Tibetan
Plateau. Adult female yaks normally breed in the warm season (July to September) and …

14-3-3 epsilon prevents G2/M transition of fertilized mouse eggs by binding with CDC25B

C Cui, X Ren, D Liu, X Deng, X Qin, X Zhao… - BMC developmental …, 2014 - Springer
Abstract Background The 14-3-3 (YWHA) proteins are highly conserved in higher
eukaryotes, participate in various cellular signaling pathways including cell cycle regulation …

Maternal transmission ratio distortion of GNAS loss‐of‐function mutations

S Snanoudj, A Molin, C Colson… - Journal of Bone and …, 2020 - academic.oup.com
ABSTRACT Pseudohypoparathyroidism type 1A (PHP1A) and
pseudopseudohypoparathyroidism (PPHP) are two rare autosomal dominant disorders …

[HTML][HTML] Knockdown of PRKAR2B results in the failure of oocyte maturation

H Yoon, H Jang, EY Kim, S Moon, S Lee… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Cyclic adenosine monophosphate (cAMP)-dependent type 2 regulatory
subunit beta (Prkar2b) is a regulatory isoform of cAMP-dependent protein kinase (PKA) …

[PDF][PDF] Single cell transcriptome profiling revealed differences in gene expression during oocyte maturation in Haimen white goats

XY Yin, GH Cheng, HY Guo, Q Wang, YJ Li… - Genet Mol …, 2017 - m.jstshuichan.com
Juvenile in vitro embryo transfer is an important animal reproductive technology that can
shorten the generation interval of livestock, explore the reproductive potential of dams with …

Protein kinase Cδ (PKCδ) involved in the regulation of pAkt1 (Ser473) on the release of mouse oocytes from diplotene arrest

L Liu, S Li, H Li, D Yu, C Li, G Li, Y Cao… - Cell Biochemistry …, 2018 - Wiley Online Library
Defects in meiotic maturation may lead to chromosome segregation errors and genomic
instability. Previous reports indicated that protein kinase C delta (PKCδ) may interact with …

Combined use of dbcAMP and IBMX minimizes the damage induced by a long‐term artificial meiotic arrest in mouse germinal vesicle oocytes

XC Wu, Z Han, X Hao, YT Zhao, CJ Zhou… - Molecular …, 2020 - Wiley Online Library
Phosphodiesterase (PDE)‐mediated reduction of cyclic adenosine monophosphate (cAMP)
activity can initiate germinal vesicle (GV) breakdown in mammalian oocytes. It is crucial to …

哺乳动物卵母细胞不对称分裂的研究进展

张俊玉, 吕珊, 牛慧敏, 雷安民 - 遗传, 2018 - chinagene.cn
哺乳动物卵母细胞成熟过程需要进行两次连续的不对称分裂, 最终形成体积差异巨大的子细胞:
大体积的卵母细胞和两种体积较小的极体. 不对称分裂现象是哺乳动物卵母细胞减数分裂的典型 …