Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Poly (amidoamine) s (PAAs) are a family of synthetic polymers obtained by stepwise
polyaddition of prim‐or sec‐amines to bisacrylamides. Nearly all conceivable …

Poly (β-aminoesters) 1− 3 were synthesized via the addition of N, N '-
dimethylethylenediamine, piperazine, and 4, 4 '-trimethylenedipiperidine to 1, 4-butanediol …

Abstract Poly (amido‐amine) s (PAAs) are synthetic tert‐amino polymers obtained by
stepwise polyaddition of primary or secondary aliphatic amines to bis (acrylamide) s. Linear …

We have examined the cytotoxicity of a number of poly (amidoamine) polymers which have
been proposed for use as DNA delivery systems and compared them to the charged …

Polyplexes are now emerging as potentially useful vectors for gene therapy. To improve our
understanding of how the chemical structure of the polymer affects the properties of these …

Linear amino polymers containing basic nitrogen atoms are critically reviewed with regard to
their synthesis, protonation and complex formation in solution with metal ions. Cross linked …

Five poly (amido-amine) s (PAAs) carrying two ter-amino groups and one carboxyl group per
repeating unit were prepared by hydrogen-transfer polyaddition of 2-methylpiperazine (ISA …

Chemical modification of poly (l‐lysine) by hydrogen transfer addition of N, N‐
dimethylacrylamide to the primary amino groups results in new water soluble derivatives …

Synthesis, physico-chemical properties and biomedical applications of poly(amidoamine)s -
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