Microbial production of advanced biofuels
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …
phenotypes has become increasingly possible due to advances in culturing techniques …
Metabolic burden: cornerstones in synthetic biology and metabolic engineering applications
Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …
Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods
Reconstructed microbial metabolic networks facilitate a mechanistic description of the
genotype–phenotype relationship through the deployment of constraint-based …
genotype–phenotype relationship through the deployment of constraint-based …
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
Growing concerns over limited fossil resources and associated environmental problems are
motivating the development of sustainable processes for the production of chemicals, fuels …
motivating the development of sustainable processes for the production of chemicals, fuels …
The biomass objective function
AM Feist, BO Palsson - Current opinion in microbiology, 2010 - Elsevier
Flux balance analysis (FBA) is a mathematical approach for analyzing the flow of
metabolites through a metabolic network. To computationally predict cell growth using FBA …
metabolites through a metabolic network. To computationally predict cell growth using FBA …
[HTML][HTML] Automating the design-build-test-learn cycle towards next-generation bacterial cell factories
Automation is playing an increasingly significant role in synthetic biology. Groundbreaking
technologies, developed over the past 20 years, have enormously accelerated the …
technologies, developed over the past 20 years, have enormously accelerated the …
Synthesis and Accumulation of Aromatic Aldehydes in an Engineered Strain of Escherichia coli
AM Kunjapur, Y Tarasova… - Journal of the American …, 2014 - ACS Publications
Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances,
and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by …
and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by …
Design and analysis of synthetic carbon fixation pathways
Carbon fixation is the process by which CO2 is incorporated into organic compounds. In
modern agriculture in which water, light, and nutrients can be abundant, carbon fixation …
modern agriculture in which water, light, and nutrients can be abundant, carbon fixation …
Reconstruction of biochemical networks in microorganisms
Abstract Systems analysis of metabolic and growth functions in microbial organisms is
rapidly developing and maturing. Such studies are enabled by reconstruction, at the …
rapidly developing and maturing. Such studies are enabled by reconstruction, at the …