Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic
selections in crop improvement. Several types of molecular markers, such as single …

The diversity of available 2nd and 3rd generation DNA sequencing platforms is increasing
rapidly. Costs for these systems range from< 100000tomorethan 1 000 000, with instrument …

Modern commercial tomato varieties are substantially less flavorful than heirloom varieties.
To understand and ultimately correct this deficiency, we quantified flavor-associated …

The ability to efficiently and accurately determine genotypes is a keystone technology in
modern genetics, crucial to studies ranging from clinical diagnostics, to genotype-phenotype …

Advances in next generation technologies have driven the costs of DNA sequencing down
to the point that genotyping-by-sequencing (GBS) is now feasible for high diversity, large …

Rapid advances in “next‐generation” DNA sequencing technology have brought the US
$1000 human (Homo sapiens) genome within reach while providing the raw sequencing …

The challenge of sequencing ancient DNA has led to the development of specialized
laboratory protocols that have focused on reducing contamination and maximizing the …

Improvements in technology have reduced the cost of DNA sequencing to the point that the
limiting factor for many experiments is the time and reagent cost of sample preparation. We …

Due to the increasing throughput of current DNA sequencing instruments, sample
multiplexing is necessary for making economical use of available sequencing capacities. A …

The identification of mutations that are present in a small fraction of DNA templates is
essential for progress in several areas of biomedical research. Although massively parallel …