Hedgehog signaling and truncated GLI1 in cancer

D Doheny, SG Manore, GL Wong, HW Lo - Cells, 2020 - mdpi.com
The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a
consequence of improper control, aberrant HH signaling results in tumorigenesis and …

[HTML][HTML] Reconnoitring signaling pathways and exploiting innovative approaches tailoring multifaceted therapies for skin cancer

D Datta, S Sultana, J Strauss, A Puri, SP Bandi… - International Journal of …, 2024 - Elsevier
Nowadays, skin cancer is widespread just like a varied malignant cancer which can cause
serious health issues. Skin cancer, which encompasses malignant melanoma, basal cell …

The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-β1 and focal adhesion kinase activation

AA Villanueva, P Sanchez-Gomez… - Cell Adhesion & …, 2021 - Taylor & Francis
Neuroblastoma is a highly metastatic tumor that emerges from neural crest cell progenitors.
Focal Adhesion Kinase (FAK) is a regulator of cell migration that binds to the receptor …

Analysis of the occurrence and distribution of primary and recurrent basal cell carcinoma of head and neck coupled to the assessment of tumor microenvironment and …

J Moisejenko-Golubovica, O Volkov… - … of Morphology and …, 2021 - pmc.ncbi.nlm.nih.gov
Often, basal cell carcinoma (BCC) displays local aggressiveness, and when developed in
the head and neck presents with deep tissue invasion and recurrence. Previous studies …

[HTML][HTML] Beyond cyclopamine: Targeting Hedgehog signaling for cancer intervention

BT Baby, AM Kulkarni, PKR Gayam… - Archives of Biochemistry …, 2024 - Elsevier
Hedgehog (Hh) signaling plays a significant role in embryogenesis and several
physiological processes, such as wound healing and organ homeostasis. In a pathological …

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells

AA Villanueva, S Puvogel, P Lois… - Cell Adhesion & …, 2019 - Taylor & Francis
Neuroblastoma (NB) is the most common pediatric extracranial solid tumor. It arises during
development of the sympathetic nervous system. Netrin-4 (NTN4), a laminin-related protein …

Relevance of humanized three-dimensional tumor tissue models: a descriptive systematic literature review

D Contartese, F Salamanna, F Veronesi… - Cellular and Molecular Life …, 2020 - Springer
Despite numerous advances in tumor screening, diagnosis, and treatment, to date, tumors
remain one of the leading causes of death, principally due to metastasis and the …

Pathogenesis of Basal Carcinoma and Features of Development of Local Recurrences in Head and Neck. Summary of the Doctoral Thesis

J Moisejenko-Goluboviča - 2023 - dspace.rsu.lv
Ultraviolet radiation is known to be a major cause of skin malignancies, including basal cell
carcinoma (BCC), the most common type of skin cancer. With frequent development in the …

Bazālo šūnu karcinomas patoģenēzes un lokālo recidīvu attīstības īpatnības galvas un kakla rajonā. Promocijas darbs

J Moisejenko-Goluboviča - 2023 - dspace.rsu.lv
Ultravioletais starojums ir pazīstams kā viens no galvenajiem ādas ļaundabīgo audzēju
izraisītājiem, tostarp bazālo šūnu karcinomas (BŠK) gadījumā, kas ir visizplatītākais ādas …

[PDF][PDF] Bioscientia Medicina: Journal of Biomedicine & Translational Research

YF Yahya, DEW Putra, CS Sovianti, D Trislinawati… - vol - pdfs.semanticscholar.org
Background: Xerosis skin and pruritus is the most commonly found in elderly with symptoms
mild to severe recurrent pruritus, the skin looks rough, scaly, fissured or cracked caused …